# GeDiPNet Cluster 316 -- Enriched Pathways -- generated 2026-10-07 20:49:20
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	KEGG	2	UST, CSGALNACT1	21	66	17.33	5.839e-3	4.847e-2
Activation of Na-permeable kainate receptors	Reactome	1	GRIK1	2	66	90.98	1.096e-2	7.246e-2
ABO blood group biosynthesis	Reactome	1	ABO	3	66	60.66	1.640e-2	9.173e-2
Axon guidance	KEGG	4	LRRC4C, NTNG1, SEMA3C, SEMA3E	183	66	3.98	1.806e-2	9.745e-2
Vasopressin regulates renal water homeostasis via Aquaporins	Reactome	2	ADCY6, RAB11FIP2	43	66	8.46	2.324e-2	1.120e-1
Glutamatergic synapse	KEGG	3	ADCY6, GRIK1, GRM4	116	66	4.71	2.587e-2	1.188e-1
Biosynthesis of maresin-like SPMs	Reactome	1	CYP2C8	6	66	30.33	3.253e-2	1.348e-1
Vascular smooth muscle contraction	KEGG	3	ADCY6, CALCB, KCNMA1	134	66	4.07	3.735e-2	1.458e-1
RUNX3 regulates CDKN1A transcription	Reactome	1	ZFHX3	7	66	26.00	3.785e-2	1.470e-1
G alpha (s) signalling events	Reactome	3	ADCY6, CALCB, PDE7B	140	66	3.90	4.166e-2	1.550e-1
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Reactome	1	CYP2C8	8	66	22.75	4.314e-2	1.580e-1
G alpha (i) signalling events	Reactome	4	CXCR5, RGS4, GRM4, RGS7	249	66	2.92	4.788e-2	1.676e-1
Ca2+ activated K+ channels	Reactome	1	KCNMA1	9	66	20.22	4.840e-2	1.685e-1
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Reactome	1	CYP2C8	9	66	20.22	4.840e-2	1.685e-1
Post-translational modification: synthesis of GPI-anchored proteins	Reactome	2	NTM, NTNG1	66	66	5.51	5.095e-2	1.732e-1