# GeDiPNet Cluster 313 -- Enriched Pathways -- generated 2026-10-08 01:37:31
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
IL-17 signaling pathway	KEGG	3	IL1B, MUC5B, IL17A	94	7	54.76	1.589e-5	5.014e-4
Inflammatory bowel disease	KEGG	2	IL1B, IL17A	66	7	51.99	6.136e-4	9.540e-3
Salivary secretion	KEGG	2	MUC5B, ADRB2	93	7	36.90	1.215e-3	1.610e-2
Rheumatoid arthritis	KEGG	2	IL1B, IL17A	95	7	36.12	1.267e-3	1.664e-2
Interleukin-4 and Interleukin-13 signaling	Reactome	2	IL1B, IL17A	108	7	31.77	1.634e-3	2.014e-2
Th17 cell differentiation	KEGG	2	IL1B, IL17A	109	7	31.48	1.664e-3	2.040e-2
Alcoholic liver disease	KEGG	2	IL1B, IL17A	144	7	23.83	2.882e-3	3.041e-2
CLEC7A/inflammasome pathway	Reactome	1	IL1B	6	7	285.95	3.493e-3	3.476e-2
Interleukin-17 signaling	Reactome	1	IL17A	8	7	214.46	4.655e-3	4.241e-2
Interleukin-1 processing	Reactome	1	IL1B	8	7	214.46	4.655e-3	4.241e-2
Adrenoceptors	Reactome	1	ADRB2	9	7	190.63	5.235e-3	4.595e-2
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)	Reactome	1	MUC5B	17	7	100.92	9.869e-3	6.949e-2
Defective GALNT12 causes colorectal cancer 1 (CRCS1)	Reactome	1	MUC5B	17	7	100.92	9.869e-3	6.949e-2
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	Reactome	1	MUC5B	18	7	95.32	1.045e-2	7.203e-2
Cytokine-cytokine receptor interaction	KEGG	2	IL1B, IL17A	298	7	11.51	1.187e-2	7.780e-2