# GeDiPNet Cluster 304 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 15:53:03
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
response to hypoxia	GO:0001666	16	KCNMA1, NPPC, SLC2A1, ABCB1, CASP3, CASP9, CHRNA4, MTHFR, NOS1, PENK, TNF, ND1	176	302	5.63	2.860e-8	4.219e-6
positive regulation of apoptotic process	GO:0043065	20	KCNMA1, RARB, CASP3, CASP9, NEUROD1, NOD1, NOTCH1, SOD1, TNF, TP53, CDKN2A, CTLA4	326	302	3.80	3.844e-7	3.747e-5
xenobiotic transport across blood-brain barrier	GO:1990962	4	ABCB1, ABCC2, ABCG2, ABCC1	6	302	41.25	9.779e-7	8.144e-5
cellular response to amyloid-beta	GO:1904646	8	APOE, ADRB2, TNF, ABCC1, ICAM1, IGF1, IGF1R, EPHA4	53	302	9.34	1.999e-6	1.442e-4
response to xenobiotic stimulus	GO:0009410	16	NPPC, ABCB1, CASP3, FOS, MTHFR, NFATC2, SLC19A1, SLC6A3, SOD1, TNF, TP53, ABCA1	248	302	3.99	2.997e-6	1.993e-4
replicative senescence	GO:0090399	5	SERPINE1, TP53, CDKN2A, ERCC1, MME	16	302	19.34	4.025e-6	2.526e-4
neurofilament bundle assembly	GO:0033693	3	NEFH, NEFL, NEFM	3	302	61.88	4.180e-6	2.598e-4
negative regulation of collagen biosynthetic process	GO:0032966	5	NPPC, NOTCH1, IL6, PPARD, IL6R	17	302	18.20	5.627e-6	3.296e-4
positive regulation of neuron apoptotic process	GO:0043525	8	GRIK2, ASCL1, CASP3, CASP9, NOS1, TNF, TP53, AIFM1	65	302	7.62	9.625e-6	5.063e-4
response to ethanol	GO:0045471	10	NPPC, CSF3, FOS, PENK, SLC6A3, SOD1, TNF, GSTP1, ND4, NTRK3	110	302	5.63	1.181e-5	5.933e-4
export across plasma membrane	GO:0140115	4	ABCB1, ABCG2, ABCA1, ABCC1	10	302	24.75	1.301e-5	6.416e-4
neurofilament cytoskeleton organization	GO:0060052	4	SOD1, NEFH, ATP8A2, NEFL	10	302	24.75	1.301e-5	6.416e-4
cellular response to hypoxia	GO:0071456	11	FOS, NOTCH1, PTGS2, TP53, PPARD, PRKCE, AIFM1, ANGPT4, GNGT1, HIF3A, LMNA	139	302	4.90	1.635e-5	7.677e-4
positive regulation of smooth muscle cell proliferation	GO:0048661	7	HES5, TNF, IGF1, IL6, CDH13, CX3CL1, IL6R	52	302	8.33	1.927e-5	8.723e-4
tetrahydrofolate metabolic process	GO:0046653	4	DHFR, MTHFR, SHMT1, TYMS	11	302	22.50	2.018e-5	9.043e-4