# GeDiPNet Cluster 30 -- Enriched Pathways -- generated 2026-10-08 06:22:25
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Pathways in cancer	KEGG	25	APC, TERT, CTNNB1, SUFU, ERBB2, BAX, BCL2, CDKN1A, CDKN1B, PRKCA, CCND1, JUN	533	79	7.13	2.310e-15	7.584e-13
MicroRNAs in cancer	KEGG	16	APC, ERBB2, BCL2, CDKN1A, CDKN1B, PRKCA, CCND1, PTGS2, CCNE1, CDK6, DNMT1, IRS2	311	79	7.82	1.376e-10	1.826e-8
Gastric cancer	KEGG	12	APC, TERT, CTNNB1, ERBB2, BAX, BCL2, CDKN1A, CDKN1B, MUC2, CCND1, CCNE1, MYC	150	79	12.16	2.309e-10	2.876e-8
Small cell lung cancer	KEGG	10	BAX, BCL2, CDKN1A, CDKN1B, CCND1, PTGS2, CCNE1, CDK6, MYC, SKP2	93	79	16.35	4.393e-10	5.115e-8
Breast cancer	KEGG	11	APC, CTNNB1, ERBB2, BAX, CDKN1A, CCND1, JUN, BRCA2, CDK6, ESR2, MYC	148	79	11.30	3.019e-9	2.910e-7
Basal cell carcinoma	KEGG	8	APC, CTNNB1, SUFU, BAX, CDKN1A, PTCH1, PTCH2, SMO	63	79	19.30	7.059e-9	6.206e-7
Epstein-Barr virus infection	KEGG	12	TNF, BAX, BCL2, CDKN1A, CDKN1B, CCND1, JUN, CCNE1, CDK6, MYC, SKP2, STAT3	204	79	8.94	7.884e-9	6.867e-7
AGE-RAGE signaling pathway in diabetic complications	KEGG	9	TNF, BAX, BCL2, CDKN1B, PRKCA, PRKCD, CCND1, JUN, STAT3	101	79	13.55	1.853e-8	1.465e-6
Non-small cell lung cancer	KEGG	8	ERBB2, BAX, CDKN1A, PRKCA, CCND1, CDK6, RASSF1, STAT3	73	79	16.66	2.324e-8	1.797e-6
Interleukin-4 and Interleukin-13 signaling	Reactome	9	TNF, BCL6, IRF4, BCL2, CDKN1A, CCND1, PTGS2, MYC, STAT3	108	79	12.67	3.345e-8	2.483e-6
Kaposi sarcoma-associated herpesvirus infection	KEGG	11	CTNNB1, CSF2, BAX, CDKN1A, CCND1, JUN, PTGS2, CDK6, MYC, PIK3CG, STAT3	196	79	8.53	5.673e-8	3.972e-6
Hedgehog signaling pathway	KEGG	7	SUFU, BCL2, CCND1, GPR161, PTCH1, PTCH2, SMO	56	79	19.00	7.277e-8	4.960e-6
Proteoglycans in cancer	KEGG	11	CTNNB1, TNF, ERBB2, CDKN1A, PRKCA, CCND1, MYC, PTCH1, SMO, STAT3, VAV1	204	79	8.20	8.544e-8	5.721e-6
Colorectal cancer	KEGG	8	APC, CTNNB1, BAX, BCL2, CDKN1A, CCND1, JUN, MYC	87	79	13.98	9.384e-8	6.210e-6
Hepatitis B	KEGG	10	TNF, BAX, BCL2, CDKN1A, PRKCA, JUN, CCNE1, DDX3X, MYC, STAT3	163	79	9.33	1.036e-7	6.753e-6