# GeDiPNet Cluster 3 -- Enriched GO Terms (Biological Process) -- generated 2026-10-09 15:58:57
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:23:08.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
regulation of heart rate by cardiac conduction	GO:0086091	35	ACE, CACNA1C, KCNH2, KCNJ2, KCNQ1, PKP2, SCN5A, CTNNA3, DSC2, DSG2, DSP, JUP	43	814	18.69	1.194e-40	1.276e-36
cardiac muscle contraction	GO:0060048	35	CASQ2, KCNH2, KCNQ1, RYR2, SCN5A, MYBPC3, MYH7, MYL3, TTN, ACTC1, DMD, MYH6	43	814	18.69	1.194e-40	1.276e-36
sarcomere organization	GO:0045214	27	ACTN2, ANKRD1, FLNC, LDB3, MYBPC3, TTN, MYH6, MYOM1, TNNT2, TPM1, PLEC, PRKAR1A	43	814	14.41	1.619e-26	6.560e-23
heart development	GO:0007507	60	CACNA1C, EDN1, GJA1, KCNQ1, PKP2, LDB3, TGFB3, ABCC9, MYL2, TNNI3, PRKAR1A, CDKN1A	273	814	5.05	7.025e-26	2.722e-22
ventricular cardiac muscle cell action potential	GO:0086005	16	KCNH2, KCNQ1, PKP2, RYR2, SCN5A, ANK2, KCNE1, GJA5, CAV3, GPD1L, KCNE3, KCNE5	17	814	21.61	2.379e-21	4.634e-18
muscle contraction	GO:0006936	30	CACNA1C, TRDN, DES, MYH7, MYL3, TTN, DMD, HCN4, MYH6, RYR1, KCND3, SLMAP	85	814	8.10	7.557e-20	1.184e-16
regulation of ventricular cardiac muscle cell membrane repolarization	GO:0060307	16	KCNH2, KCNQ1, SCN5A, ANK2, KCNE1, GJA5, AKAP9, CACNA2D1, CAV3, KCNE3, KCNE5, SCN1B	21	814	17.49	2.416e-18	2.938e-15
regulation of heart rate	GO:0002027	20	CALM1, CALM2, CALM3, CASQ2, KCNQ1, RYR2, SCN5A, MYH7, ANK2, DMD, HCN4, MYH6	39	814	11.77	1.518e-17	1.637e-14
cardiac muscle cell action potential involved in contraction	GO:0086002	16	CACNA1C, KCNJ2, PKP2, SCN5A, KCNE1, SCN10A, CACNA2D1, SCN1B, SCN2B, SCN3B, KCNE2, SCN4B	24	814	15.30	7.721e-17	7.459e-14
membrane repolarization during ventricular cardiac muscle cell action potential	GO:0098915	12	KCNH2, KCNQ1, KCNE1, KCNJ5, DLG1, KCND3, KCNE3, KCNE5, KCNJ8, SCN2B, KCNE2, KCNJ3	13	814	21.19	5.390e-16	4.493e-13
regulation of ventricular cardiac muscle cell action potential	GO:0098911	11	CACNA1C, PKP2, RYR2, CTNNA3, DSC2, DSG2, DSP, JUP, TRPM4, CAV1, DLG1	11	814	22.96	1.004e-15	7.798e-13
regulation of the force of heart contraction	GO:0002026	13	PLN, MYH7, MYL3, MYH6, MYL2, CAV1, CAMK2D, CSRP3, GRK2, MYL4, GAA, SLC9A1	19	814	15.71	3.942e-14	2.341e-11
vasodilation	GO:0042311	19	ACE, KNG1, ABCC9, GJA5, KCNJ8, INS, TNF, ADORA2A, BDKRB2, NOS3, NPPB, PPARD	50	814	8.72	9.596e-14	5.254e-11
regulation of cardiac muscle contraction	GO:0055117	14	CALM1, CALM2, CALM3, RYR2, SCN5A, ANK2, HCN4, TNNI3K, GJA5, NKX2-5, SCN10A, CAV3	24	814	13.39	1.037e-13	5.636e-11
positive regulation of gene expression	GO:0010628	62	AVP, GJA1, LMNA, TTN, ACTC1, ANK2, MYOM1, CAV1, CDK6, MYOCD, NKX2-5, IFNG	504	814	2.82	1.353e-13	7.194e-11