# GeDiPNet Cluster 29 -- Enriched Pathways -- generated 2026-10-07 18:52:49
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Interleukin-4 and Interleukin-13 signaling	Reactome	5	IL6, MMP9, NOS2, TNF, CCL2	108	37	15.03	1.857e-5	5.640e-4
TNF signaling pathway	KEGG	5	DAB2IP, IL6, MMP9, TNF, CCL2	119	37	13.64	2.969e-5	8.269e-4
Fluid shear stress and atherosclerosis	KEGG	5	PLAT, GSTT1, MMP9, TNF, CCL2	141	37	11.51	6.693e-5	1.616e-3
Complement and coagulation cascades	KEGG	4	PLAT, MBL2, PLAU, F7	88	37	14.75	1.478e-4	3.076e-3
IL-17 signaling pathway	KEGG	4	IL6, MMP9, TNF, CCL2	94	37	13.81	1.907e-4	3.771e-3
Chagas disease	KEGG	4	IL6, NOS2, TNF, CCL2	103	37	12.61	2.711e-4	4.958e-3
Interleukin-10 signaling	Reactome	3	IL6, TNF, CCL2	47	37	20.72	3.976e-4	6.675e-3
Malaria	KEGG	3	IL6, TNF, CCL2	50	37	19.48	4.775e-4	7.695e-3
Lipid and atherosclerosis	KEGG	5	CYP1A1, IL6, MMP9, TNF, CCL2	216	37	7.51	4.900e-4	7.851e-3
Eicosanoids	Reactome	2	CYP4F3, CYP4F8	12	37	54.10	5.978e-4	9.160e-3
Dissolution of Fibrin Clot	Reactome	2	PLAT, PLAU	13	37	49.94	7.051e-4	1.043e-2
Fatty acids	Reactome	2	CYP4F3, CYP4F8	15	37	43.28	9.455e-4	1.301e-2
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Reactome	2	CYP4F3, CYP4F8	20	37	32.46	1.694e-3	2.020e-2
Pertussis	KEGG	3	IL6, NOS2, TNF	78	37	12.48	1.747e-3	2.068e-2
RHO GTPases activate PAKs	Reactome	2	MYL9, MYLK	23	37	28.23	2.243e-3	2.484e-2