# GeDiPNet Cluster 272 -- Enriched Pathways -- generated 2026-10-07 04:05:48
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
LDL remodeling	Reactome	2	APOB, CETP	3	203	39.44	8.434e-4	1.192e-2
Cholesterol metabolism	KEGG	5	ABCG5, ANGPTL4, APOB, APOE, CETP	51	203	5.80	1.641e-3	1.977e-2
Chylomicron clearance	Reactome	2	APOB, APOE	5	203	23.67	2.749e-3	2.890e-2
Elastic fibre formation	Reactome	3	FBN1, FBN2, ITGAV	18	203	9.86	3.219e-3	3.239e-2
DARPP-32 events	Reactome	3	PDE4D, PPP1R1B, PPP2R1B	19	203	9.34	3.776e-3	3.617e-2
Scavenging by Class F Receptors	Reactome	2	SCARF1, APOB	6	203	19.72	4.078e-3	3.820e-2
Lysine degradation	KEGG	5	ALDH2, HYKK, PRDM2, KMT2E, SETDB2	63	203	4.70	4.172e-3	3.882e-2
Regulation of FOXO transcriptional activity by acetylation	Reactome	2	SIRT3, FOXO3	7	203	16.90	5.646e-3	4.747e-2
Dopaminergic synapse	KEGG	7	CAMK2B, DRD4, GNAQ, PPP1R1B, PPP2R1B, PPP2R3A, SLC6A3	132	203	3.14	7.082e-3	5.508e-2
Chylomicron remodeling	Reactome	2	APOB, APOE	9	203	13.15	9.465e-3	6.632e-2
Chylomicron assembly	Reactome	2	APOB, APOE	9	203	13.15	9.465e-3	6.632e-2
HDL remodeling	Reactome	2	APOE, CETP	10	203	11.83	1.170e-2	7.536e-2
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	Reactome	2	SIRT3, FOXO3	10	203	11.83	1.170e-2	7.536e-2
Scavenging by Class A Receptors	Reactome	2	APOB, APOE	11	203	10.76	1.414e-2	8.408e-2
Defective FMO3 causes Trimethylaminuria (TMAU)	Reactome	1	FMO3	1	203	59.16	1.690e-2	9.372e-2