# GeDiPNet Cluster 267 -- Enriched Pathways -- generated 2026-10-09 14:37:06
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	Reactome	2	GJA1, TUBA3C	18	45	29.65	2.022e-3	2.295e-2
Defective MAN1B1 causes MRT15	Reactome	1	MAN1B1	1	45	266.89	3.747e-3	3.579e-2
Defective PMM2 causes PMM2-CDG (CDG-1a)	Reactome	1	PMM2	1	45	266.89	3.747e-3	3.579e-2
Regulation of gap junction activity	Reactome	1	GJA1	3	45	88.96	1.120e-2	7.438e-2
Synthesis of GDP-mannose	Reactome	1	PMM2	3	45	88.96	1.120e-2	7.438e-2
SUMOylation of DNA methylation proteins	Reactome	1	DNMT1	4	45	66.72	1.491e-2	8.818e-2
Assembly and cell surface presentation of NMDA receptors	Reactome	1	GRIN3A	6	45	44.48	2.228e-2	1.115e-1
Nef and signal transduction	Reactome	1	DOCK2	8	45	33.36	2.959e-2	1.309e-1
Ca2+ activated K+ channels	Reactome	1	KCNN2	9	45	29.65	3.323e-2	1.401e-1
RNA degradation	KEGG	2	EXOSC9, DDX6	78	45	6.84	3.443e-2	1.424e-1
Formation of annular gap junctions	Reactome	1	GJA1	11	45	24.26	4.047e-2	1.561e-1
Gap junction	KEGG	2	GJA1, TUBA3C	89	45	6.00	4.376e-2	1.627e-1
Gap junction degradation	Reactome	1	GJA1	12	45	22.24	4.407e-2	1.631e-1
Purine salvage	Reactome	1	DGUOK	13	45	20.53	4.765e-2	1.709e-1
mRNA decay by 5' to 3' exoribonuclease	Reactome	1	DDX6	14	45	19.06	5.122e-2	1.774e-1