# GeDiPNet Cluster 266 -- Enriched Pathways -- generated 2026-10-07 10:53:17
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Primary immunodeficiency	KEGG	4	AICDA, CD40, CD40LG, UNG	38	9	140.47	1.061e-8	9.178e-7
Chronic myeloid leukemia	KEGG	4	BCR, ABL1, CRKL, MAPK1	77	9	69.32	1.921e-7	1.155e-5
Intestinal immune network for IgA production	KEGG	3	AICDA, CD40, CD40LG	50	9	80.07	5.604e-6	2.082e-4
Viral myocarditis	KEGG	3	ABL1, CD40, CD40LG	70	9	57.19	1.553e-5	4.848e-4
ErbB signaling pathway	KEGG	3	ABL1, CRKL, MAPK1	86	9	46.55	2.887e-5	8.078e-4
Frs2-mediated activation	Reactome	2	CRKL, MAPK1	12	9	222.41	3.282e-5	9.001e-4
Toxoplasmosis	KEGG	3	MAPK1, CD40, CD40LG	112	9	35.74	6.367e-5	1.553e-3
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Reactome	2	CD40, CD40LG	18	9	148.27	7.591e-5	1.791e-3
Neurotrophin signaling pathway	KEGG	3	ABL1, CRKL, MAPK1	120	9	33.36	7.821e-5	1.833e-3
Asthma	KEGG	2	CD40, CD40LG	32	9	83.40	2.447e-4	4.576e-3
RHO GTPases Activate WASPs and WAVEs	Reactome	2	ABL1, MAPK1	36	9	74.14	3.104e-4	5.511e-3
Allograft rejection	KEGG	2	CD40, CD40LG	39	9	68.43	3.646e-4	6.246e-3
Pathways in cancer	KEGG	4	BCR, ABL1, CRKL, MAPK1	533	9	10.01	4.043e-4	6.758e-3
Lipid and atherosclerosis	KEGG	3	MAPK1, CD40, CD40LG	216	9	18.53	4.449e-4	7.276e-3
Malaria	KEGG	2	CD40, CD40LG	50	9	53.38	6.002e-4	9.193e-3