# GeDiPNet Cluster 26 -- Top Shared Genes -- generated 2026-10-08 08:39:33
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-08 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
MYO7A	10	19	Auditory neuropathy; Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
CDH23	9	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
PCDH15	9	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
MYO6	8	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
OTOF	8	19	Auditory neuropathy; Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TECTA	8	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
USH1C	8	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
WFS1	8	19	Auditory neuropathy; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
COCH	7	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
COL11A2	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
ESPN	7	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
GJB2	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
LHFPL5	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
MARVELD2	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
MYH14	7	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
MYO15A	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
OTOA	7	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
PJVK	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TMC1	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TMIE	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TMPRSS3	7	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
WHRN	7	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
ACTG1	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
ATP11A	6	19	Auditory neuropathy; autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
CDC14A	6	19	Congenital ear anomaly; Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
CEACAM16	6	19	Congenital ear anomaly; Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
CIB2	6	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
CLDN14	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
COL11A1	6	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Meniere disease; Nonsyndromic hearing loss
ESRRB	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
EYA4	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
GRHL2	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
GSDME	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
HGF	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
KCNQ4	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
LOXHD1	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
LRTOMT	6	19	autosomal recessive nonsyndromic hearing loss 63; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
MYH9	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; Nonsyndromic hearing loss
MYO3A	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
OTOG	6	19	Deafness; Hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
OTOGL	6	19	Deafness; Hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
POU4F3	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
RDX	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
RIPOR2	6	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
SERPINB6	6	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss; Usher syndrome
SLC17A8	6	19	Auditory neuropathy; Deafness; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
SLC26A4	6	19	Congenital ear anomaly; Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
STRC	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TBC1D24	6	19	Auditory neuropathy; Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TNC	6	19	Deafness; Hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TPRN	6	19	Congenital ear anomaly; Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TRIOBP	6	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Meniere disease; Nonsyndromic hearing loss
ABCC1	5	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
ADCY1	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
ADGRV1	5	19	Congenital ear anomaly; Deafness; Hearing loss; Meniere disease; Usher syndrome
ATP2B2	5	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
C10ORF105	5	19	Congenital ear anomaly; Deafness; Hearing loss; Meniere disease; Usher syndrome
CABP2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
CCDC50	5	19	Deafness; Hereditary hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
CLRN2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
DCDC2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
DIABLO	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
DIAPH1	5	19	Auditory neuropathy; Deafness; Hearing loss; Hereditary hearing loss; Nonsyndromic hearing loss
DMXL2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
ELMOD3	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
EPS8	5	19	autosomal recessive nonsyndromic hearing loss 102; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
EPS8L2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; Meniere disease; nonsyndromic genetic hearing loss
GIPC3	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
GJB3	5	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
GJB6	5	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
GRXCR1	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
GRXCR2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
ILDR1	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
KARS1	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
LMX1A	5	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
MET	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
MINAR2	5	19	Deafness; Hearing loss; hearing loss, autosomal recessive 120; Isolated sensorineural deafness; Nonsyndromic hearing loss
MSRB3	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
PDE1C	5	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
PLS1	5	19	autosomal dominant nonsyndromic hearing loss; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
PTPRQ	5	19	Congenital ear anomaly; Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
S1PR2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
SIX1	5	19	Deafness; Hearing loss; Hereditary hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
SLC26A5	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
SLC44A4	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
SYNE4	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TBCEL-TECTA	5	19	Congenital ear anomaly; Deafness; Hearing loss; Meniere disease; Nonsyndromic hearing loss
TJP2	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
TMTC4	5	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss; Worster drought syndrome
AFG2B	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
BDP1	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss
CD164	4	19	autosomal dominant nonsyndromic hearing loss; Deafness; Isolated sensorineural deafness; Nonsyndromic hearing loss
CLIC5	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
CRYM	4	19	Deafness; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
DIAPH3	4	19	Auditory neuropathy; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
FOXI1	4	19	Deafness; Hearing loss; Hereditary hearing loss; Nonsyndromic hearing loss
GPR156	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
GRAP	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss
HOMER2	4	19	Deafness; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
KITLG	4	19	Deafness; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
MCM2	4	19	Deafness; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
MITF	4	19	Congenital ear anomaly; Deafness; Hearing loss; Isolated sensorineural deafness
MPZL2	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss
MYO1A	4	19	Deafness; Hearing loss; Hereditary hearing loss; Nonsyndromic hearing loss
NARS2	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss
OSBPL2	4	19	Deafness; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
P2RX2	4	19	Deafness; Isolated sensorineural deafness; nonsyndromic genetic hearing loss; Nonsyndromic hearing loss
PDZD7	4	19	Congenital ear anomaly; Deafness; Hearing loss; Usher syndrome
PNPT1	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
ROR1	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; nonsyndromic genetic hearing loss
STX4	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
TRRAP	4	19	Deafness; Hearing loss; Isolated sensorineural deafness; Nonsyndromic hearing loss
USH2A	4	19	Congenital ear anomaly; Deafness; Hearing loss; Usher syndrome
AIFM1	3	19	Auditory neuropathy; Congenital ear anomaly; Hearing loss
BSND	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
CACNA1D	3	19	Deafness; Hearing loss; Meniere disease
CEP78	3	19	Cone rod dystrophy and hearing loss; Hearing loss; Usher syndrome
COL4A4	3	19	Hearing loss; Meniere disease; Usher syndrome
ESRP1	3	19	Deafness; Hearing loss; nonsyndromic genetic hearing loss
GPSM2	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
GREB1L	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
MAP1B	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
MYO1C	3	19	Isolated sensorineural deafness; Meniere disease; Nonsyndromic hearing loss
PAX3	3	19	Deafness; Hearing loss; Usher syndrome
PKHD1L1	3	19	Deafness; Isolated sensorineural deafness; Nonsyndromic hearing loss
POU3F4	3	19	Congenital ear anomaly; Hereditary hearing loss; nonsyndromic genetic hearing loss
PPIP5K2	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
RAB33A	3	19	Auditory neuropathy; Congenital ear anomaly; Hearing loss
SLITRK6	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
SMPX	3	19	Hearing loss; Hereditary hearing loss; nonsyndromic genetic hearing loss
SPNS2	3	19	Deafness; Hearing loss; hearing loss, autosomal recessive 115
THOC1	3	19	Deafness; Hearing loss; Nonsyndromic hearing loss
TMEM132E	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
TSPEAR	3	19	Deafness; Hearing loss; Nonsyndromic hearing loss
USH1G	3	19	Deafness; Hearing loss; Usher syndrome
USP48	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
WBP2	3	19	Deafness; Hearing loss; Isolated sensorineural deafness
ACAN	2	19	Hearing loss; Meniere disease
ANKRD24	2	19	Hearing loss; Nonsyndromic hearing loss
ARHGEF28	2	19	Hearing loss; Meniere disease
ATOH1	2	19	Deafness; Hearing loss
ATP6V1B1	2	19	Hearing loss; Usher syndrome
B3GNT4	2	19	Deafness; Hearing loss
CEP250	2	19	Cone rod dystrophy and hearing loss; Usher syndrome
CLCC1	2	19	Deafness; Hearing loss
CLCNKA	2	19	Deafness; Hearing loss
CLDN9	2	19	Deafness; Hearing loss
CLRN1	2	19	Hearing loss; Usher syndrome
COL9A3	2	19	Hearing loss; Nonsyndromic hearing loss
CRYL1	2	19	Deafness; Hearing loss
EDNRB	2	19	Deafness; Hearing loss
EPHA10	2	19	Deafness; Hearing loss
FSCN2	2	19	Hearing loss; Meniere disease
FTO	2	19	Hearing loss; Meniere disease
GAB1	2	19	Deafness; Nonsyndromic hearing loss
GAS2	2	19	Deafness; Hearing loss
HARS2	2	19	Hearing loss; Usher syndrome
HLA-B	2	19	Hearing loss; Meniere disease
HLA-DRB1	2	19	Hearing loss; Meniere disease
KCNJ10	2	19	Deafness; Nonsyndromic hearing loss
KCNQ1	2	19	Congenital ear anomaly; Hearing loss
MACF1	2	19	Isolated sensorineural deafness; Nonsyndromic hearing loss
MANBA	2	19	Hearing loss; Meniere disease
NEFL	2	19	Auditory neuropathy; Hearing loss
PDE6A	2	19	PDE6A-related retinopathy; Usher syndrome
PI4KB	2	19	Deafness; Hearing loss
PSAP	2	19	Deafness; Usher syndrome
REST	2	19	Deafness; Nonsyndromic hearing loss
SCD5	2	19	Deafness; Hearing loss
SLC12A2	2	19	Deafness; Hearing loss
SLC19A2	2	19	Congenital ear anomaly; Hearing loss
SLC52A2	2	19	Auditory neuropathy; Hearing loss
SYNJ2	2	19	Hearing loss; Meniere disease
TIMM8A	2	19	Auditory neuropathy; Deafness dystonia syndrome
TOMT	2	19	Deafness; Hearing loss
TWNK	2	19	Auditory neuropathy; Nonsyndromic hearing loss