# GeDiPNet Cluster 251 -- Enriched GO Terms (Biological Process) -- generated 2026-10-09 13:16:10
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:23:08.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
response to cocaine	GO:0042220	5	CRH, DRD2, OPRK1, PITX3, SLC6A3	35	68	39.26	1.639e-7	1.827e-5
synaptic transmission, dopaminergic	GO:0001963	4	COMT, CRH, DRD2, ADORA2A	15	68	73.28	2.123e-7	2.277e-5
signal transduction	GO:0007165	23	ANK3, CCR6, CCR7, CRH, CRHR1, CRHR2, DRD2, GJA1, HTR1A, MAPK1, MC4R, OPRK1	2125	68	2.97	8.315e-7	7.113e-5
fear response	GO:0042596	3	COMT, CRHR1, ADRA2A	8	68	103.05	2.547e-6	1.756e-4
G protein-coupled receptor signaling pathway	GO:0007186	15	CCR6, CCR7, CRHR1, CRHR2, DRD2, HTR1A, KCNK2, MC4R, OPRK1, VIP, ADORA2A, ADRA2A	1031	68	4.00	3.400e-6	2.221e-4
phospholipase C-activating G protein-coupled receptor signaling pathway	GO:0007200	6	DRD2, OPRK1, RASGRP4, GAP43, ADORA2A, CCKBR	120	68	13.74	4.891e-6	2.975e-4
glutamate secretion	GO:0014047	3	GJA1, KCNK2, NTRK2	11	68	74.95	7.447e-6	4.173e-4
dopamine catabolic process	GO:0042420	3	COMT, SLC6A3, MAOA	11	68	74.95	7.447e-6	4.173e-4
cellular response to cocaine	GO:0071314	3	COMT, CRH, SLC1A3	11	68	74.95	7.447e-6	4.173e-4
cell communication by electrical coupling involved in cardiac conduction	GO:0086064	3	ATP1A3, CACNA1C, GJA1	12	68	68.70	9.904e-6	5.221e-4
regulation of serotonin secretion	GO:0014062	2	CRH, HTR1A	2	68	274.81	1.305e-5	6.472e-4
response to nicotine	GO:0035094	4	DRD2, MAPK1, OPRK1, SLC6A3	40	68	27.48	1.328e-5	6.563e-4
positive regulation of gene expression	GO:0010628	10	ANK3, CRH, GJA1, SLC6A4, NTRK2, CALCOCO1, CLU, INS, PKP1, SMAD1	504	68	5.45	1.332e-5	6.578e-4
prepulse inhibition	GO:0060134	3	DRD2, SLC6A3, ADORA2A	14	68	58.89	1.630e-5	7.707e-4
chemical synaptic transmission	GO:0007268	7	CRH, HTR1A, MAPK1, OPRK1, SLC17A7, SLC1A3, GRM7	236	68	8.15	2.361e-5	1.021e-3