# GeDiPNet Cluster 247 -- Enriched Pathways -- generated 2026-10-08 18:43:07
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Hedgehog 'off' state	Reactome	2	IFT140, PTCH1	56	7	61.28	4.418e-4	7.396e-3
TFAP2 (AP-2) family regulates transcription of other transcription factors	Reactome	1	PITX2	4	7	428.93	2.330e-3	2.607e-2
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Reactome	1	PAX6	7	7	245.10	4.074e-3	3.881e-2
Ligand-receptor interactions	Reactome	1	PTCH1	7	7	245.10	4.074e-3	3.881e-2
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Reactome	1	PAX6	14	7	122.55	8.133e-3	6.161e-2
Extracellular matrix organization	Reactome	1	COL4A1	15	7	114.38	8.712e-3	6.435e-2
Anchoring fibril formation	Reactome	1	COL4A1	15	7	114.38	8.712e-3	6.435e-2
Activation of SMO	Reactome	1	PTCH1	18	7	95.32	1.045e-2	7.203e-2
Crosslinking of collagen fibrils	Reactome	1	COL4A1	18	7	95.32	1.045e-2	7.203e-2
NCAM1 interactions	Reactome	1	COL4A1	21	7	81.70	1.218e-2	7.914e-2
Non-integrin membrane-ECM interactions	Reactome	1	COL4A1	24	7	71.49	1.391e-2	8.546e-2
Maturity onset diabetes of the young	KEGG	1	PAX6	26	7	65.99	1.506e-2	8.969e-2
Laminin interactions	Reactome	1	COL4A1	28	7	61.28	1.621e-2	9.420e-2
Signaling by PDGF	Reactome	1	COL4A1	33	7	51.99	1.908e-2	1.033e-1
Collagen chain trimerization	Reactome	1	COL4A1	44	7	38.99	2.537e-2	1.213e-1