# GeDiPNet Cluster 242 -- Enriched Pathways -- generated 2026-10-10 07:30:11
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-10 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
FGFR1c and Klotho ligand binding and activation	Reactome	1	KL	3	29	138.05	7.227e-3	5.770e-2
Ligand-receptor interactions	Reactome	1	PTCH1	7	29	59.16	1.678e-2	9.684e-2
ECM-receptor interaction	KEGG	2	FRAS1, FREM2	89	29	9.31	1.936e-2	1.051e-1
Longevity regulating pathway	KEGG	2	EHMT2, KL	90	29	9.20	1.977e-2	1.062e-1
Prostanoid ligand receptors	Reactome	1	PTGER2	9	29	46.02	2.153e-2	1.115e-1
Inflammatory mediator regulation of TRP channels	KEGG	2	PTGER2, TRPV3	99	29	8.37	2.363e-2	1.179e-1
SLBP independent Processing of Histone Pre-mRNAs	Reactome	1	LSM10	10	29	41.41	2.389e-2	1.185e-1
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Reactome	1	LSM10	11	29	37.65	2.625e-2	1.249e-1
Aspartate and asparagine metabolism	Reactome	1	ASPA	12	29	34.51	2.861e-2	1.307e-1
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Reactome	1	PERP	14	29	29.58	3.330e-2	1.420e-1
ADORA2B mediated anti-inflammatory cytokines production	Reactome	2	GNB5, PTGER2	128	29	6.47	3.794e-2	1.520e-1
Phospholipase C-mediated cascade: FGFR1	Reactome	1	KL	16	29	25.88	3.797e-2	1.520e-1
Trafficking of GluR2-containing AMPA receptors	Reactome	1	GRIP1	17	29	24.36	4.029e-2	1.571e-1
G beta:gamma signalling through BTK	Reactome	1	GNB5	18	29	23.01	4.261e-2	1.623e-1
Activation of SMO	Reactome	1	PTCH1	18	29	23.01	4.261e-2	1.623e-1