# GeDiPNet Cluster 236 -- Enriched Pathways -- generated 2026-10-08 07:15:24
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Cytosolic DNA-sensing pathway	KEGG	4	ADAR, SAMHD1, TREX1, STING1	83	12	48.23	1.006e-6	4.887e-5
DNA replication	KEGG	3	RNASEH2A, RNASEH2B, RNASEH2C	36	12	83.40	5.342e-6	2.050e-4
RIG-I-like receptor signaling pathway	KEGG	3	ADAR, IFIH1, STING1	72	12	41.70	4.372e-5	1.164e-3
IRF3-mediated induction of type I IFN	Reactome	2	TREX1, STING1	13	12	153.97	7.095e-5	1.713e-3
Regulation by TREX1	Reactome	1	TREX1	1	12	1000.83	9.992e-4	1.390e-2
Nucleobase catabolism	Reactome	1	SAMHD1	1	12	1000.83	9.992e-4	1.390e-2
Coronavirus disease - COVID-19	KEGG	3	ADAR, IFIH1, STING1	238	12	12.62	1.481e-3	1.879e-2
Interferon alpha/beta signaling	Reactome	2	ADAR, SAMHD1	67	12	29.88	1.952e-3	2.285e-2
C6 deamination of adenosine	Reactome	1	ADAR	2	12	500.42	1.997e-3	2.322e-2
Formation of editosomes by ADAR proteins	Reactome	1	ADAR	2	12	500.42	1.997e-3	2.322e-2
STAT6-mediated induction of chemokines	Reactome	1	STING1	3	12	333.61	2.995e-3	3.114e-2
STING mediated induction of host immune responses	Reactome	1	STING1	5	12	200.17	4.987e-3	4.437e-2
Measles	KEGG	2	ADAR, IFIH1	139	12	14.40	8.135e-3	6.162e-2
SLBP independent Processing of Histone Pre-mRNAs	Reactome	1	LSM11	10	12	100.08	9.951e-3	6.966e-2
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Reactome	1	LSM11	11	12	90.98	1.094e-2	7.412e-2