# GeDiPNet Cluster 222 -- Pairs Within Cluster -- generated 2026-10-07 20:09:19
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 17:17:47.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome	Seborrhea-like dermatitis with psoriasiform elements	0.50000	2	2.531e-8	1.932e-7
Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome	Kenny caffey syndrome	0.50000	1	6.494e-5	2.317e-4
Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome	Sanjad-sakati syndrome	0.50000	1	6.494e-5	2.317e-4
Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome	encephalopathy, progressive, with amyotrophy and optic atrophy	0.50000	1	6.494e-5	2.317e-4
encephalopathy, progressive, with amyotrophy and optic atrophy	Kenny caffey syndrome	0.50000	1	6.494e-5	2.317e-4
encephalopathy, progressive, with amyotrophy and optic atrophy	Sanjad-sakati syndrome	0.50000	1	6.494e-5	2.317e-4
Kenny caffey syndrome	Sanjad-sakati syndrome	0.50000	1	6.494e-5	2.317e-4
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome	Kenny caffey syndrome	0.25000	1	1.948e-4	5.325e-4
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome	Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome	0.25000	1	1.948e-4	5.325e-4
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome	Sanjad-sakati syndrome	0.25000	1	1.948e-4	5.325e-4
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome	encephalopathy, progressive, with amyotrophy and optic atrophy	0.25000	1	1.948e-4	5.325e-4
Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome	Kenny-caffey syndrome	0.25000	1	1.948e-4	5.325e-4
encephalopathy, progressive, with amyotrophy and optic atrophy	Kenny-caffey syndrome	0.25000	1	1.948e-4	5.325e-4
Kenny caffey syndrome	Kenny-caffey syndrome	0.25000	1	1.948e-4	5.325e-4
Kenny-caffey syndrome	Sanjad-sakati syndrome	0.25000	1	1.948e-4	5.325e-4
Kenny-caffey syndrome	muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 11	0.25000	1	1.948e-4	5.325e-4