# GeDiPNet Cluster 210 -- Enriched Pathways -- generated 2026-10-07 14:43:08
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Pancreatic secretion	KEGG	7	CPA1, PRSS1, PRSS2, CFTR, CCK, CA2, CEL	102	60	13.74	6.915e-7	3.531e-5
Bile secretion	KEGG	6	CFTR, ABCB4, ABCG5, ABCG8, CA2, UGT1A7	90	60	13.34	5.414e-6	2.023e-4
Defective ABCG8 causes gallbladder disease 4 and sitosterolemia	Reactome	2	ABCG5, ABCG8	2	60	200.17	2.454e-5	7.065e-4
Defective ABCG5 causes sitosterolemia	Reactome	2	ABCG5, ABCG8	2	60	200.17	2.454e-5	7.065e-4
ABC transporters	KEGG	4	CFTR, ABCB4, ABCG5, ABCG8	45	60	17.79	7.196e-5	1.713e-3
Neuroactive ligand-receptor interaction	KEGG	9	PRSS1, PRSS2, ADRB2, CCK, CNR1, CNR2, HTR4, SST, TRPV1	370	60	4.87	8.356e-5	1.938e-3
Interleukin-10 signaling	Reactome	4	CCL2, CCL5, PTGS2, IL1RN	47	60	17.04	8.550e-5	1.975e-3
Influenza A	KEGG	6	PRSS1, PRSS2, CCL2, CCL5, HLA-DQA1, HLA-DRB1	173	60	6.94	2.153e-4	4.142e-3
Hormone signaling	KEGG	6	GNA11, ADRB2, CCK, INS, SST, PTHLH	219	60	5.48	7.562e-4	1.100e-2
Fat digestion and absorption	KEGG	3	ABCG5, ABCG8, CEL	43	60	13.97	1.269e-3	1.621e-2
Rheumatoid arthritis	KEGG	4	CCL2, CCL5, HLA-DQA1, HLA-DRB1	95	60	8.43	1.277e-3	1.629e-2
Type I diabetes mellitus	KEGG	3	HLA-DQA1, HLA-DRB1, INS	44	60	13.65	1.357e-3	1.705e-2
Cholesterol metabolism	KEGG	3	ABCG5, ABCG8, LPL	51	60	11.77	2.082e-3	2.349e-2
Regulation of lipolysis in adipocytes	KEGG	3	ADRB2, INS, PTGS2	59	60	10.18	3.159e-3	3.196e-2
Platelet degranulation 	Reactome	4	ALB, HGF, SERPINA1, SERPING1	123	60	6.51	3.283e-3	3.285e-2