# GeDiPNet Cluster 21 -- Enriched GO Terms (Biological Process) -- generated 2026-10-09 04:55:54
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:23:08.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
positive regulation of transcription by RNA polymerase II	GO:0045944	294	MRTFB, AHR, ESR1, FGFR2, ABL1, ACVR1, AKT1, AR, ATM, BMP2, BMP4, BMPR2	1208	1863	2.44	2.401e-51	5.292e-47
negative regulation of apoptotic process	GO:0043066	171	AKT1, AKT2, ANGPTL4, ARAF, ARHGDIA, AURKA, BAG1, BARD1, BCL2, BCL2A1, BIRC2, BIRC5	524	1863	3.27	1.482e-47	2.488e-43
positive regulation of gene expression	GO:0010628	160	ACTA2, AGR2, AKT1, AR, ATM, BMP2, BMP4, BMPR2, BRCA1, CAV1, CD74, CDH5	504	1863	3.18	9.175e-43	1.138e-38
positive regulation of cell population proliferation	GO:0008284	160	FGFR2, ADAM10, AR, AREG, BCAR3, BCL2, BIRC5, BMP2, BMP4, CCND1, CDKN1B, CSF1	532	1863	3.02	1.841e-39	1.855e-35
negative regulation of transcription by RNA polymerase II	GO:0000122	226	ESR1, FGFR2, AR, BMP2, BMP4, C1QBP, CASP7, CAV1, CCND1, CCNE1, CDKN2A, CTNNB1	1002	1863	2.26	1.209e-33	9.070e-30
apoptotic process	GO:0006915	183	AHR, CHEK2, FGFR2, ABL1, ADAR, AFP, AKT1, AKT2, AURKA, BAG1, BAX, BCL2	747	1863	2.46	5.647e-32	3.620e-28
positive regulation of cell migration	GO:0030335	100	ACVR1, ADAM10, AKT1, AKT2, ATM, BMP2, BMP4, CASP8, CAV1, CDH5, CLDN1, CLDN4	292	1863	3.44	5.487e-30	3.023e-26
negative regulation of cell population proliferation	GO:0008285	128	ADAMTS1, AR, BAP1, BAX, BCHE, BCL2, BMP2, BMP4, BMPR2, CAV1, CDH5, CDKN1B	444	1863	2.89	1.128e-29	6.027e-26
positive regulation of MAPK cascade	GO:0043410	85	FGFR2, AR, BCAR3, BMP2, CD40, CD74, CDH2, CTNNB1, EFNA1, EGF, EGFR, ERBB2	224	1863	3.81	2.715e-29	1.408e-25
positive regulation of DNA-templated transcription	GO:0045893	182	AHR, CHEK2, ESR1, ACVR1, AR, ARID1A, BIRC2, BMP2, BMP4, BRCA1, BRCA2, CD74	778	1863	2.35	4.024e-29	2.027e-25
response to xenobiotic stimulus	GO:0009410	87	AHR, ABCB1, ABCC1, ABL1, ACACB, BCAR3, BCHE, BCL2, CAT, CCND1, CDH1, CENPF	248	1863	3.52	4.385e-27	1.933e-23
negative regulation of gene expression	GO:0010629	101	ESR1, ADAM10, AKT1, AURKA, BMP2, BMP4, CTNNB1, CXCL8, DLL4, DNMT1, EZH2, FBXW7	339	1863	2.99	7.834e-25	2.606e-21
response to hypoxia	GO:0001666	68	ABCB1, ANGPTL4, BIRC2, BMP2, CAT, CAV1, COMT, CPT1A, CXCL12, CXCR4, CYP1A1, DIO3	176	1863	3.88	3.275e-24	9.871e-21
positive regulation of apoptotic process	GO:0043065	97	ABL1, ATM, BARD1, BAX, BCL2, BCL2A1, BMP2, BMP4, C1QBP, CASP8, CDKN2A, CTNNB1	326	1863	2.98	7.591e-24	2.194e-20
cell population proliferation	GO:0008283	84	AKT1, BAP1, BAX, BCL2, BMP4, BRCA2, CAV1, CCND1, CSF1R, CSF2, CTNNB1, EGF	263	1863	3.20	4.690e-23	1.190e-19