# GeDiPNet Cluster 21 -- Top Shared Genes -- generated 2026-10-07 23:31:41
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-08 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
IL18	9	20	Allergic contact dermatitis; Atopic dermatitis; Autoimmune hepatitis; Behcet disease; Contact dermatitis; Giant cell arteritis; Glomerulonephritis; Hypersensitivity; Rhinitis
IL10	8	20	Allergic contact dermatitis; Atopic dermatitis; Autoimmune hepatitis; Behcet disease; Glomerulonephritis; Hypersensitivity; Rhinitis; Uveitis
IL4	8	20	Allergic contact dermatitis; Atopic dermatitis; Autoimmune hepatitis; Behcet disease; Dermatitis; Giant cell arteritis; Hypersensitivity; Rhinitis
TNF	8	20	Allergic contact dermatitis; Atopic dermatitis; Behcet disease; Dermatitis; Glomerulonephritis; Hypersensitivity; Rhinitis; Uveitis
HLA-DRB1	7	20	Autoimmune hepatitis; Behcet disease; Dermatitis; Eosinophilia; Giant cell arteritis; Hypersensitivity; Uveitis
IFNG	7	20	Allergic contact dermatitis; Atopic dermatitis; Autoimmune hepatitis; Giant cell arteritis; Glomerulonephritis; Hypersensitivity; Rhinitis
TLR4	7	20	Allergic contact dermatitis; Atopic dermatitis; Behcet disease; Contact dermatitis; Eosinophilia; Giant cell arteritis; Rhinitis
HLA-DQA1	6	20	Autoimmune hepatitis; Dermatitis; Eosinophilia; Glomerulonephritis; Hypersensitivity; Rhinitis
IL13	6	20	Atopic dermatitis; Autoimmune hepatitis; Dermatitis; Hypersensitivity; Rhinitis; Uveitis
IL1B	6	20	Atopic dermatitis; Behcet disease; Glomerulonephritis; Hypersensitivity; Rhinitis; Uveitis
IL2	6	20	Allergic contact dermatitis; Atopic dermatitis; Autoimmune hepatitis; Behcet disease; Glomerulonephritis; Rhinitis
TGFB1	6	20	Atopic dermatitis; Autoimmune hepatitis; Behcet disease; Eosinophilia; Hypersensitivity; Uveitis
CCL2	5	20	Autoimmune hepatitis; Behcet disease; Giant cell arteritis; Glomerulonephritis; Hypersensitivity
CYP1A1	5	20	Allergic contact dermatitis; Atopic dermatitis; Behcet disease; Contact dermatitis; Hypersensitivity
HLA-B	5	20	Behcet disease; Dermatitis; Giant cell arteritis; Hypersensitivity; Uveitis
IL6	5	20	Atopic dermatitis; Autoimmune hepatitis; Glomerulonephritis; Hypersensitivity; Uveitis
ALB	4	20	Glomerulonephritis; Hypersensitivity; Rhinitis; Uveitis
CCR1	4	20	Allergic contact dermatitis; Behcet disease; Contact dermatitis; Hypersensitivity
CCR2	4	20	Allergic contact dermatitis; Hypersensitivity; Rhinitis; Uveitis
CXCR3	4	20	Atopic dermatitis; Contact dermatitis; Glomerulonephritis; Hypersensitivity
EMSY	4	20	Atopic dermatitis; Dermatitis; Eosinophilia; Rhinitis
HLA-DQB1	4	20	Autoimmune hepatitis; Behcet disease; Hypersensitivity; Rhinitis
IL5	4	20	Allergic contact dermatitis; Atopic dermatitis; Autoimmune hepatitis; Eosinophilia
MBL2	4	20	Atopic dermatitis; Behcet disease; Giant cell arteritis; Rhinitis
TLR2	4	20	Atopic dermatitis; Behcet disease; Eosinophilia; Rhinitis
AHR	3	20	Atopic dermatitis; Behcet disease; Contact dermatitis
CCL24	3	20	Atopic dermatitis; Hypersensitivity; Rhinitis
CCL5	3	20	Atopic dermatitis; Autoimmune hepatitis; Glomerulonephritis
CCR3	3	20	Atopic dermatitis; Behcet disease; Rhinitis
CCR5	3	20	Atopic dermatitis; Behcet disease; Uveitis
CLEC16A	3	20	Dermatitis; Eosinophilia; Rhinitis
CTLA4	3	20	Atopic dermatitis; Autoimmune hepatitis; Behcet disease
DSG1	3	20	Dermatitis; Eosinophilia; Hypersensitivity
FCGR3A	3	20	Behcet disease; Giant cell arteritis; Rhinitis
FLG	3	20	Atopic dermatitis; Contact dermatitis; Dermatitis
IL17A	3	20	Giant cell arteritis; Hypersensitivity; Rhinitis
IL23R	3	20	Behcet disease; Rhinitis; Uveitis
IL2RA	3	20	Allergic contact dermatitis; Dermatitis; Glomerulonephritis
ITGB2	3	20	Behcet disease; Dermatitis; Hypersensitivity
MS4A2	3	20	Atopic dermatitis; Hypersensitivity; Rhinitis
NAT2	3	20	Allergic contact dermatitis; Atopic dermatitis; Behcet disease
NOD2	3	20	Behcet disease; Dermatitis; Rhinitis
SERPINE1	3	20	Behcet disease; Glomerulonephritis; Rhinitis
SHARPIN	3	20	Autoinflammation with episodic fever and immune dysregulation; Dermatitis; Eosinophilia
TNFRSF1A	3	20	Behcet disease; Hypersensitivity; Uveitis
TSLP	3	20	Atopic dermatitis; Eosinophilia; Hypersensitivity
VDR	3	20	Atopic dermatitis; Autoimmune hepatitis; Behcet disease
ABCB1	2	20	Behcet disease; Rhinitis
ALK	2	20	Behcet disease; Glomerulonephritis
BCL2	2	20	Allergic contact dermatitis; Contact dermatitis
BDNF	2	20	Atopic dermatitis; Rhinitis
CAPSL	2	20	Dermatitis; Rhinitis
CASP8	2	20	Allergic contact dermatitis; Contact dermatitis
CAT	2	20	Behcet disease; Rhinitis
CCL11	2	20	Atopic dermatitis; Hypersensitivity
CCL17	2	20	Atopic dermatitis; Hypersensitivity
CCL19	2	20	Allergic contact dermatitis; Hypersensitivity
CCL26	2	20	Eosinophilia; Rhinitis
CCL3	2	20	Glomerulonephritis; Hypersensitivity
CCL4	2	20	Glomerulonephritis; Hypersensitivity
CCL7	2	20	Glomerulonephritis; Hypersensitivity
CDH19	2	20	Glomerulonephritis; Microscopic polyangiitis
CLDN1	2	20	Atopic dermatitis; Contact dermatitis
CNDP1	2	20	Carnosinemia; Glomerulonephritis
CXCL1	2	20	Autoimmune hepatitis; Hypersensitivity
CXCL8	2	20	Behcet disease; Glomerulonephritis
CYP2D6	2	20	Autoimmune hepatitis; Rhinitis
EGFR	2	20	Behcet disease; Dermatitis
ERAP1	2	20	Behcet disease; Uveitis
F2	2	20	Autoimmune hepatitis; Glomerulonephritis
FAS	2	20	Behcet disease; Glomerulonephritis
GLB1	2	20	Atopic dermatitis; Contact dermatitis
GSTP1	2	20	Atopic dermatitis; Contact dermatitis
GTPBP2	2	20	Eosinophilia; jaberi-elahi syndrome
HLA-A	2	20	Dermatitis; Uveitis
HMOX1	2	20	Contact dermatitis; Rhinitis
HNMT	2	20	Atopic dermatitis; Rhinitis
IL1A	2	20	Allergic contact dermatitis; Behcet disease
IL1RN	2	20	Glomerulonephritis; Rhinitis
IL21R	2	20	Behcet disease; Giant cell arteritis
IL33	2	20	Atopic dermatitis; Hypersensitivity
IL4R	2	20	Atopic dermatitis; Rhinitis
KLF13	2	20	Eosinophilia; Glomerulonephritis
LEP	2	20	Autoimmune hepatitis; Rhinitis
MRC1	2	20	Allergic contact dermatitis; Rhinitis
MTHFR	2	20	Glomerulonephritis; Hypersensitivity
NRXN1	2	20	Eosinophilia; Glomerulonephritis
OTOL1	2	20	Eosinophilia; Glomerulonephritis
PHYKPL	2	20	Glomerulonephritis; phosphohydroxylysinuria
PTPN22	2	20	Behcet disease; Giant cell arteritis
PTPRD	2	20	Behcet disease; Eosinophilia
S100A8	2	20	Atopic dermatitis; Contact dermatitis
SELE	2	20	Allergic contact dermatitis; Atopic dermatitis
SELP	2	20	Atopic dermatitis; Hypersensitivity
SLC11A1	2	20	Atopic dermatitis; Behcet disease
SLC25A24	2	20	Eosinophilia; fontaine progeroid syndrome
SMAD3	2	20	Eosinophilia; Rhinitis
SPP1	2	20	Allergic contact dermatitis; Hypersensitivity
ST6GAL1	2	20	Allergic contact dermatitis; Eosinophilia
STAT4	2	20	Autoimmune hepatitis; Behcet disease
STAT6	2	20	Atopic dermatitis; Eosinophilia
TLR7	2	20	Allergic contact dermatitis; systemic lupus erythematosus 17
TXNRD1	2	20	Contact dermatitis; Lewis lung carcinoma
VEGFA	2	20	Contact dermatitis; Glomerulonephritis
WDR36	2	20	Eosinophilia; Rhinitis