# GeDiPNet Cluster 192 -- Enriched Pathways -- generated 2026-10-08 09:12:05
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Insulin secretion	KEGG	2	RIMS2, CACNA1F	86	7	39.90	1.040e-3	1.431e-2
Amine ligand-binding receptors	Reactome	1	GPR143	7	7	245.10	4.074e-3	3.881e-2
Calcium signaling pathway	KEGG	2	CACNA1F, PHKA2	254	7	13.51	8.722e-3	6.436e-2
Glycogen breakdown (glycogenolysis)	Reactome	1	PHKA2	16	7	107.23	9.291e-3	6.693e-2
Phase 2 - plateau phase	Reactome	1	CACNA1F	25	7	68.63	1.448e-2	8.761e-2
Phase 0 - rapid depolarisation	Reactome	1	CACNA1F	44	7	38.99	2.537e-2	1.213e-1
Cortisol synthesis and secretion	KEGG	1	CACNA1F	65	7	26.40	3.728e-2	1.490e-1
GnRH secretion	KEGG	1	CACNA1F	65	7	26.40	3.728e-2	1.490e-1
Renin secretion	KEGG	1	CACNA1F	69	7	24.87	3.954e-2	1.537e-1
Arrhythmogenic right ventricular cardiomyopathy	KEGG	1	CACNA1F	86	7	19.95	4.907e-2	1.730e-1
Cardiac muscle contraction	KEGG	1	CACNA1F	87	7	19.72	4.963e-2	1.742e-1
GABAergic synapse	KEGG	1	CACNA1F	89	7	19.28	5.075e-2	1.757e-1
GnRH signaling pathway	KEGG	1	CACNA1F	93	7	18.45	5.297e-2	1.797e-1
Aldosterone synthesis and secretion	KEGG	1	CACNA1F	98	7	17.51	5.575e-2	1.844e-1
Hypertrophic cardiomyopathy	KEGG	1	CACNA1F	99	7	17.33	5.631e-2	1.855e-1