# GeDiPNet Cluster 17 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 13:30:48
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
positive regulation of gene expression	GO:0010628	14	ACTA2, KRAS, HRAS, MAP2K1, VDR, ATM, TP53, APP, NFE2L2, NOTCH1, OCLN, PSEN1	504	67	7.75	2.379e-9	4.813e-7
negative regulation of gene expression	GO:0010629	12	HRAS, RB1, MAP2K1, PIK3CA, TP53, MAPT, APOE, APP, NOTCH1, OCLN, PSEN1, PPARG	339	67	9.87	2.566e-9	5.143e-7
intracellular phosphate ion homeostasis	GO:0030643	4	FGF23, SLC34A3, ENPP1, SLC34A1	10	67	111.56	3.118e-8	4.537e-6
positive regulation of ERK1 and ERK2 cascade	GO:0070374	9	ACTA2, FGF23, FGFR3, HRAS, MAP2K1, TEK, APOE, APP, NOTCH1	201	67	12.49	4.018e-8	5.634e-6
thyroid gland development	GO:0030878	5	MAP2K1, CGA, PAX8, NKX2-1, FOXE1	30	67	46.49	6.766e-8	8.744e-6
positive regulation of neuron apoptotic process	GO:0043525	6	CASP10, CASP8, FASLG, ATM, TP53, APP	65	67	25.75	1.182e-7	1.389e-5
positive regulation of apoptotic process	GO:0043065	10	CASP8, FAS, FASLG, CTLA4, ATM, TP53, APC, APP, NOTCH1, PSEN1	326	67	8.56	2.339e-7	2.469e-5
Ras protein signal transduction	GO:0007265	6	NRAS, RASGRP1, KRAS, HRAS, RB1, TP53	79	67	21.18	3.826e-7	3.734e-5
positive regulation of amyloid fibril formation	GO:1905908	3	APOE, APP, PSEN1	5	67	167.35	4.383e-7	4.182e-5
positive regulation of DNA-templated transcription	GO:0045893	14	FGF23, GLI2, MAP2K1, TP53, AHR, APOE, MECOM, NFE2L2, NOTCH1, PSEN1, PAX8, PPARG	778	67	5.02	5.260e-7	4.871e-5
positive regulation of transcription by RNA polymerase II	GO:0045944	17	HRAS, RB1, GLI2, VDR, ATM, MAFF, TP53, AHR, APP, MECOM, NFE2L2, NOTCH1	1208	67	3.93	8.266e-7	7.104e-5
thymus development	GO:0048538	5	MAP2K1, ATM, TYR, PSEN1, FOXE1	50	67	27.89	9.519e-7	7.981e-5
neuron apoptotic process	GO:0051402	6	KRAS, HRAS, RB1, ATM, TP53, PSEN1	98	67	17.08	1.374e-6	1.068e-4
cellular senescence	GO:0090398	5	PRKCD, HRAS, MAP2K1, ATM, TP53	57	67	24.47	1.845e-6	1.351e-4
apoptotic process	GO:0006915	13	CASP10, CASP8, FAS, FASLG, PRKCD, FGFR3, RB1, TP53, AHR, APP, MECOM, NOTCH1	747	67	4.85	2.068e-6	1.476e-4