# GeDiPNet Cluster 166 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 03:55:56
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
melanin biosynthetic process from tyrosine	GO:0006583	3	SLC45A2, TYR, OCA2	4	126	111.23	1.191e-6	9.646e-5
melanin biosynthetic process	GO:0042438	4	MC1R, SLC45A2, TYR, OCA2	14	126	42.37	1.872e-6	1.391e-4
positive regulation of T cell mediated cytotoxicity	GO:0001916	4	IL23R, TAP2, HLA-B, HLA-C	34	126	17.45	7.813e-5	2.580e-3
developmental pigmentation	GO:0048066	3	SLC45A2, GNA11, OCA2	14	126	31.78	1.032e-4	3.170e-3
epidermis development	GO:0008544	6	KLK7, GRHL3, LCE3A, LCE3B, PLOD1, TP63	114	126	7.81	1.227e-4	3.588e-3
type II interferon-mediated signaling pathway	GO:0060333	3	TYK2, IRF1, TP53	15	126	29.66	1.284e-4	3.720e-3
negative regulation of macrophage colony-stimulating factor signaling pathway	GO:1902227	2	PTPN2, STAP1	3	126	98.87	1.347e-4	3.853e-3
antigen processing and presentation of peptide antigen via MHC class I	GO:0002474	3	ERAP1, HLA-B, HLA-C	17	126	26.17	1.899e-4	4.980e-3
regulation of interleukin-12 production	GO:0032655	2	FOXP1, HLA-B	4	126	74.15	2.682e-4	6.328e-3
inflammatory response	GO:0006954	11	IL13, IL23R, IL2RA, NOS2, PRDX5, TNFAIP3, TNIP1, TRAF3IP2, TACR1, TLR2, TMEM258	467	126	3.49	3.245e-4	7.231e-3
intracellular signal transduction	GO:0035556	11	MC1R, TYK2, FYN, PLCL2, SOCS1, TRAF3IP2, PLCD1, MAST4, CORO2A, DEPDC4, PLCB4	471	126	3.46	3.488e-4	7.628e-3
macrophage activation	GO:0042116	3	FOXP1, IL13, JMJD6	23	126	19.34	4.803e-4	9.502e-3
lysosomal lumen pH elevation	GO:0035752	2	SLC45A2, OCA2	6	126	49.44	6.647e-4	1.182e-2
interleukin-23-mediated signaling pathway	GO:0038155	2	IL23R, TYK2	6	126	49.44	6.647e-4	1.182e-2
positive regulation of T cell proliferation	GO:0042102	4	IL23R, IL2RA, TYK2, CCDC88B	67	126	8.85	1.088e-3	1.620e-2