# GeDiPNet Cluster 163 -- Enriched Pathways -- generated 2026-10-07 19:52:33
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Regulation of gene expression by Hypoxia-inducible Factor	Reactome	2	EPO, VEGFA	11	14	155.97	6.899e-5	1.654e-3
IL-17 signaling pathway	KEGG	3	IL17A, MUC5B, TNF	94	14	27.38	1.588e-4	3.255e-3
Rheumatoid arthritis	KEGG	3	IL17A, VEGFA, TNF	95	14	27.09	1.638e-4	3.339e-3
Interleukin-4 and Interleukin-13 signaling	Reactome	3	IL17A, VEGFA, TNF	108	14	23.83	2.395e-4	4.503e-3
Cytokine-cytokine receptor interaction	KEGG	4	IL17A, EPO, TNF, IL1RN	298	14	11.51	3.055e-4	5.443e-3
Interleukin-10 signaling	Reactome	2	TNF, IL1RN	47	14	36.50	1.324e-3	1.674e-2
Transcriptional activation of mitochondrial biogenesis	Reactome	2	IDH2, SOD2	51	14	33.64	1.557e-3	1.900e-2
Human cytomegalovirus infection	KEGG	3	VEGFA, TAP1, TNF	226	14	11.39	2.053e-3	2.327e-2
Signaling by VEGF	Reactome	1	VEGFA	2	14	428.93	2.330e-3	2.554e-2
Inflammatory bowel disease	KEGG	2	IL17A, TNF	66	14	26.00	2.594e-3	2.771e-2
Renin secretion	KEGG	2	ADRB2, ACE	69	14	24.87	2.831e-3	2.950e-2
Antigen processing and presentation	KEGG	2	TAP1, TNF	81	14	21.18	3.879e-3	3.691e-2
Peroxisome	KEGG	2	IDH2, SOD2	83	14	20.67	4.069e-3	3.813e-2
Salivary secretion	KEGG	2	ADRB2, MUC5B	93	14	18.45	5.081e-3	4.421e-2
Hypertrophic cardiomyopathy	KEGG	2	TNF, ACE	99	14	17.33	5.739e-3	4.803e-2