# GeDiPNet Cluster 16 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 02:23:36
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
positive regulation of gene expression	GO:0010628	73	CTSH, DTNBP1, PTPN22, SMAD3, TICAM1, TLR3, TP53, VDR, ZBTB7B, SMO, ATM, ATF2	504	1077	2.51	2.670e-13	1.386e-10
response to lipopolysaccharide	GO:0032496	33	CASP8, FOXP1, GPX4, PTPN22, RAC1, TICAM1, DIO2, DUSP10, EDN1, GJB6, LITAF, SPON2	161	1077	3.56	1.417e-10	3.934e-8
positive regulation of transcription by RNA polymerase II	GO:0045944	122	AHR, BCL2L12, CD200, GRHL1, IKZF4, IRF4, MAFF, MC1R, PIK3R1, PPARGC1B, SBNO2, SMAD3	1208	1077	1.75	5.867e-10	1.403e-7
negative regulation of transcription by RNA polymerase II	GO:0000122	106	BACH2, CBFA2T2, CUX1, DUSP22, FOXP1, JARID2, JAZF1, JDP2, MAFF, OVOL1, RALY, SLA2	1002	1077	1.84	6.864e-10	1.604e-7
positive regulation of miRNA transcription	GO:1902895	18	SMAD3, TERT, TP53, IL6, JUN, MYCN, TGFB2, NOTCH2, IL10, TNF, NGFR, PAX6	56	1077	5.58	1.125e-9	2.489e-7
positive regulation of cell population proliferation	GO:0008284	67	CEP43, KRT6A, TSPYL5, SMO, EDN1, IGF2BP1, IL6, MARCKSL1, SOX4, TBX1, TGFB2, PDGFRA	532	1077	2.19	1.278e-9	2.795e-7
regulation of gene expression	GO:0010468	55	AHR, FOXP1, JARID2, MC1R, ZBTB7B, SMO, ATM, BAP1, GLI2, PIK3CA, ROCK1, SHH	402	1077	2.37	2.094e-9	4.305e-7
antigen processing and presentation	GO:0019882	16	CTSH, CTSS, HLA-B, HLA-C, HLA-DPA1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, RAB5B, HLA-DOB, HLA-DQB2	48	1077	5.78	5.201e-9	9.657e-7
cell population proliferation	GO:0008283	41	BRCA2, JARID2, KANK1, OCA2, SMAD3, TP53, TYR, SMO, BAP1, CAV1, ERBB2, JUN	263	1077	2.70	5.657e-9	1.044e-6
negative regulation of apoptotic process	GO:0043066	64	BCL2L12, CFL1, DSTYK, PIK3R1, PRDX5, SMAD3, TERT, TP53, RASA1, SMO, ERBB2, IL6	524	1077	2.12	1.013e-8	1.728e-6
melanin biosynthetic process	GO:0042438	9	ASIP, MC1R, OCA2, SLC45A2, TYR, MFSD12, SLC24A5, TYRP1, PMEL	14	1077	11.15	1.045e-8	1.779e-6
liver development	GO:0001889	21	JARID2, SMAD3, ARID5B, ATF2, JUN, PIK3CA, NOTCH2, UGT1A10, UGT1A7, UGT1A8, UGT1A9, SOD2	87	1077	4.19	1.536e-8	2.478e-6
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	GO:0002504	9	HLA-DPA1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DOB, HLA-DQB2, HLA-DOA, HLA-DRB5	15	1077	10.41	2.479e-8	3.747e-6
positive regulation of DNA-templated transcription	GO:0045893	83	AHR, BRCA2, HLA-DRB1, IRF4, RAI1, SMAD3, TP53, PTCH1, SMO, ARID5B, CHD3, CREB5	778	1077	1.85	3.763e-8	5.318e-6
positive regulation of nitric oxide biosynthetic process	GO:0045429	14	SMAD3, TICAM1, EDN1, IL1B, PTGS2, PTX3, SOD2, TNF, CLU, IFNG, KLRK1, TLR4	42	1077	5.78	4.742e-8	6.494e-6