# GeDiPNet Cluster 159 -- Pairs Within Cluster -- generated 2026-10-07 00:39:19
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Chilblain lupus	Chilblain lupus erythematosus	0.50000	3	1.644e-11	1.876e-10
Chilblain lupus erythematosus	Retinal vasculopathy with cerebral leukodystrophy	0.28571	2	2.530e-7	1.745e-6
Cadasil	Retinal vasculopathy with cerebral leukodystrophy	0.25000	2	3.795e-7	2.527e-6
Cadasil	Chilblain lupus erythematosus	0.20000	2	1.265e-6	7.704e-6
TREX1-related type 1 interferonopathy	Type i interferonopathy	0.50000	1	6.494e-5	2.342e-4
retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	TREX1-related type 1 interferonopathy	0.50000	1	6.494e-5	2.342e-4
retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	Type i interferonopathy	0.50000	1	6.494e-5	2.342e-4
Deoxyguanosine kinase deficiency	SAMHD1-related type 1 interferonopathy	0.33333	1	1.299e-4	3.898e-4
Chilblain lupus	retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	0.25000	1	1.948e-4	5.278e-4
Chilblain lupus	TREX1-related type 1 interferonopathy	0.25000	1	1.948e-4	5.278e-4
Chilblain lupus	Type i interferonopathy	0.25000	1	1.948e-4	5.278e-4
Retinal vasculopathy with cerebral leukodystrophy	Type i interferonopathy	0.25000	1	1.948e-4	5.278e-4
Retinal vasculopathy with cerebral leukodystrophy	TREX1-related type 1 interferonopathy	0.25000	1	1.948e-4	5.278e-4
Chilblain lupus	SAMHD1-related type 1 interferonopathy	0.25000	1	1.948e-4	5.278e-4
Retinal vasculopathy with cerebral leukodystrophy	retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	0.25000	1	1.948e-4	5.278e-4
Chilblain lupus erythematosus	SAMHD1-related type 1 interferonopathy	0.16667	1	3.247e-4	7.577e-4
Chilblain lupus erythematosus	retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	0.16667	1	3.247e-4	7.577e-4
Chilblain lupus erythematosus	TREX1-related type 1 interferonopathy	0.16667	1	3.247e-4	7.577e-4
Chilblain lupus erythematosus	Type i interferonopathy	0.16667	1	3.247e-4	7.577e-4
Chilblain lupus	Deoxyguanosine kinase deficiency	0.20000	1	3.896e-4	8.521e-4
Cadasil	TREX1-related type 1 interferonopathy	0.14286	1	3.897e-4	8.521e-4
Cadasil	Type i interferonopathy	0.14286	1	3.897e-4	8.521e-4
Chilblain lupus erythematosus	Deoxyguanosine kinase deficiency	0.14286	1	6.494e-4	1.219e-3