# GeDiPNet Cluster 14 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 15:00:11
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
nervous system development	GO:0007399	45	ACTL6B, ARHGEF2, ATXN3, CHRNA3, CNTN4, DCTN1, DISC1, ELP3, ERBB4, GSK3A, GSK3B, KALRN	631	492	2.71	1.434e-9	3.010e-7
mitochondrion organization	GO:0007005	17	CAV2, CHCHD10, GSK3B, MFN1, MFN2, PNPT1, PPARGC1A, SOD2, BCL2L1, PARK7, ATP7A, CNTNAP1	130	492	4.97	5.607e-8	7.449e-6
amyloid-beta clearance by cellular catabolic process	GO:0150094	5	ABCA7, TREM2, LDLR, MME, IDE	8	492	23.74	6.503e-7	5.874e-5
cellular response to oxidative stress	GO:0034599	14	CCS, GSR, NFE2L2, PNPT1, PPARGC1A, SETX, SLC11A2, SOD1, SOD2, PENK, PARK7, NAGLU	111	492	4.79	1.302e-6	1.037e-4
positive regulation of gene expression	GO:0010628	33	ALDH1A2, CAV1, EGR1, GSK3A, GSK3B, NFE2L2, PPARGC1A, SEC16B, TP53, TREM2, VDR, CLU	504	492	2.49	1.632e-6	1.241e-4
neurofilament cytoskeleton organization	GO:0060052	5	ARHGEF28, NEFH, NEFL, SOD1, INA	10	492	18.99	2.801e-6	1.929e-4
myelination	GO:0042552	11	FIG4, MAPK1, TNFRSF21, MPZ, CNTNAP1, EGR2, MTMR2, PMP22, SBF2, HEXB, NFASC	73	492	5.72	3.073e-6	2.075e-4
regulation of neuron apoptotic process	GO:0043523	7	EGR1, SARM1, SIGMAR1, TP53, UBB, PARK7, TRIM2	26	492	10.23	3.580e-6	2.344e-4
positive regulation of cholesterol efflux	GO:0010875	7	ABCA7, APOE, CAV1, PON1, TREM2, RXRA, ABCG1	27	492	9.85	4.724e-6	2.916e-4
negative regulation of neuron apoptotic process	GO:0043524	16	GRN, PPARGC1A, SOD1, SOD2, BCL2L1, CLU, CNTF, PARK7, AARS1, ATP7A, NGF, NTRK1	160	492	3.80	5.216e-6	3.164e-4
neuron apoptotic process	GO:0051402	12	PPARGC1A, SPG11, TNFRSF21, TP53, BCL2L1, XIAP, AARS1, COL6A3, ATP7A, NGF, NTRK1, HTRA2	98	492	4.65	1.012e-5	5.347e-4
response to toxic substance	GO:0009636	11	GSTP1, NEFL, PON1, PON2, PON3, SCFD1, FOS, PENK, AIFM1, SCN11A, SCN9A	83	492	5.03	1.100e-5	5.695e-4
postsynaptic intermediate filament cytoskeleton organization	GO:0099185	3	NEFH, NEFL, INA	3	492	37.98	1.814e-5	8.441e-4
lactone catabolic process	GO:1901335	3	PON1, PON2, PON3	3	492	37.98	1.814e-5	8.441e-4
neuron cellular homeostasis	GO:0070050	7	CHMP2B, CLCN3, DCTN1, DISC1, ATP7A, DNAJB2, HEXB	33	492	8.06	1.982e-5	9.053e-4