# GeDiPNet Cluster 13 -- Pairs Within Cluster -- generated 2026-10-07 02:47:44
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:00:13.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Charcot-marie-tooth disease	Hereditary motor and sensory neuropathies	0.43165	60	1.023e-123	1.622e-121
Dejerine-sottas disease	Roussy-levy syndrome	0.97436	38	4.118e-115	6.091e-113
Dejerine-sottas disease	Hypertrophic neuropathy	0.97436	38	4.118e-115	6.091e-113
Hypertrophic neuropathy	Roussy-levy syndrome	0.97436	38	4.118e-115	6.091e-113
Dejerine-sottas disease	Peroneal muscle atrophy	0.95000	38	1.606e-113	2.313e-111
Hypertrophic neuropathy	Peroneal muscle atrophy	0.95000	38	1.606e-113	2.313e-111
Peroneal muscle atrophy	Roussy-levy syndrome	0.95000	38	1.606e-113	2.313e-111
Dejerine-sottas disease	Hereditary motor and sensory neuropathies	0.56716	38	1.406e-96	1.549e-94
Hereditary motor and sensory neuropathies	Hypertrophic neuropathy	0.56716	38	1.406e-96	1.549e-94
Hereditary motor and sensory neuropathies	Roussy-levy syndrome	0.56716	38	1.406e-96	1.549e-94
Hereditary motor and sensory neuropathies	Peroneal muscle atrophy	0.55882	38	5.473e-95	5.716e-93
Amyotrophic lateral sclerosis	Motor neuron disease	0.17784	61	2.753e-93	2.721e-91
Charcot-marie-tooth disease	Dejerine-sottas disease	0.28571	38	8.098e-82	6.864e-80
Charcot-marie-tooth disease	Roussy-levy syndrome	0.28571	38	8.098e-82	6.864e-80
Charcot-marie-tooth disease	Hypertrophic neuropathy	0.28571	38	8.098e-82	6.864e-80
Charcot-marie-tooth disease	Peroneal muscle atrophy	0.28358	38	3.139e-80	2.631e-78
Distal hereditary motor neuropathy	Distal spinal muscular atrophy	0.41667	20	2.685e-48	1.416e-46
Charcot-marie-tooth disease	Distal hereditary motor neuropathy	0.18182	26	3.166e-47	1.642e-45
Distal spinal muscular atrophy	Hereditary motor and sensory neuropathies	0.25641	20	1.464e-41	6.749e-40
Distal hereditary motor neuropathy	Hereditary motor and sensory neuropathies	0.21176	18	1.609e-34	6.021e-33
Distal hereditary motor neuropathy	Spinal muscular atrophy	0.25424	15	1.029e-31	3.494e-30
Dejerine-sottas disease	Distal spinal muscular atrophy	0.20690	12	1.004e-24	2.556e-23
Distal spinal muscular atrophy	Hypertrophic neuropathy	0.20690	12	1.004e-24	2.556e-23
Distal spinal muscular atrophy	Roussy-levy syndrome	0.20690	12	1.004e-24	2.556e-23
Charcot-marie-tooth disease	Spinal muscular atrophy	0.10390	16	3.687e-24	9.109e-23
Distal spinal muscular atrophy	Spinal muscular atrophy	0.18966	11	2.437e-22	5.419e-21
Dejerine-sottas disease	Distal hereditary motor neuropathy	0.13636	9	1.096e-16	1.859e-15
Hereditary motor and sensory neuropathies	Motor neuron disease	0.09524	12	1.409e-16	2.368e-15
Congenital pes cavus	Roussy-levy syndrome	0.15909	7	2.436e-16	4.019e-15
Congenital pes cavus	Hypertrophic neuropathy	0.15909	7	2.436e-16	4.019e-15
Congenital pes cavus	Dejerine-sottas disease	0.15909	7	2.436e-16	4.019e-15
Congenital pes cavus	Peroneal muscle atrophy	0.15556	7	2.968e-16	4.871e-15
Hereditary motor and sensory neuropathies	Spinal muscular atrophy	0.10638	10	3.264e-16	5.348e-15
Distal spinal muscular atrophy	Motor neuron disease	0.09574	9	1.036e-14	1.538e-13
Distal hereditary motor neuropathy	Motor neuron disease	0.09091	9	4.751e-14	6.673e-13
Dejerine-sottas disease	Spinal muscular atrophy	0.10145	7	3.030e-12	3.675e-11
Charcot-marie-tooth disease, x-linked	Roussy-levy syndrome	0.11905	5	3.878e-12	4.658e-11
Charcot-marie-tooth disease, x-linked	Hypertrophic neuropathy	0.11905	5	3.878e-12	4.658e-11
Charcot-marie-tooth disease, x-linked	Dejerine-sottas disease	0.11905	5	3.878e-12	4.658e-11
Charcot-marie-tooth disease, x-linked	Peroneal muscle atrophy	0.11628	5	4.448e-12	5.327e-11
Dejerine-sottas disease	Motor neuron disease	0.07843	8	5.961e-12	7.097e-11
Amyotrophic lateral sclerosis	Charcot-marie-tooth disease	0.04260	19	5.929e-11	6.386e-10
Charcot-Marie-Tooth disease type 2	Hereditary motor and sensory neuropathies	0.02985	2	1.809e-5	9.132e-5
Charcot-Marie-Tooth disease X-linked dominant 6	Charcot-marie-tooth disease, x-linked	0.11111	1	5.195e-4	1.041e-3
Charcot-marie-tooth disease, x-linked	neuronopathy, distal hereditary motor, autosomal recessive 5	0.11111	1	5.195e-4	1.041e-3
Charcot-Marie-Tooth disease type 4B3	Charcot-marie-tooth disease, x-linked	0.11111	1	5.195e-4	1.041e-3
Charcot-marie-tooth disease, x-linked	X-linked hereditary motor and sensory neuropathy	0.11111	1	5.195e-4	1.041e-3
Charcot-Marie-Tooth disease type 2D	Congenital pes cavus	0.07692	1	7.793e-4	1.386e-3
Charcot-Marie-Tooth disease type 2	Congenital pes cavus	0.07143	1	1.558e-3	2.360e-3
Charcot-Marie-Tooth disease type 2D	Distal spinal muscular atrophy	0.03125	1	2.013e-3	2.885e-3
Distal hereditary motor neuropathy	neuronopathy, distal hereditary motor, autosomal recessive 5	0.02703	1	2.338e-3	3.233e-3
Charcot-Marie-Tooth disease type 2D	Distal hereditary motor neuropathy	0.02703	1	2.338e-3	3.233e-3
neuronopathy, distal hereditary motor, autosomal recessive 5	Spinal muscular atrophy	0.02632	1	2.403e-3	3.301e-3
Spinal muscular atrophy	Vexas syndrome	0.02632	1	2.403e-3	3.301e-3
Charcot-Marie-Tooth disease type 2D	Spinal muscular atrophy	0.02632	1	2.403e-3	3.301e-3
Charcot-Marie-Tooth disease axonal type 2P	Roussy-levy syndrome	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease axonal type 2P	Hypertrophic neuropathy	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease axonal type 2P	Dejerine-sottas disease	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease type 2D	Dejerine-sottas disease	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease type 4B3	Dejerine-sottas disease	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease type 4B3	Hypertrophic neuropathy	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease type 4B3	Roussy-levy syndrome	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease X-linked dominant 6	Dejerine-sottas disease	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease X-linked dominant 6	Hypertrophic neuropathy	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease X-linked dominant 6	Roussy-levy syndrome	0.02564	1	2.468e-3	3.358e-3
Charcot-Marie-Tooth disease X-linked dominant 6	Peroneal muscle atrophy	0.02500	1	2.533e-3	3.435e-3
Charcot-Marie-Tooth disease type 4B3	Peroneal muscle atrophy	0.02500	1	2.533e-3	3.435e-3
Charcot-Marie-Tooth disease axonal type 2P	Peroneal muscle atrophy	0.02500	1	2.533e-3	3.435e-3
Charcot-Marie-Tooth disease type 2	Distal spinal muscular atrophy	0.03030	1	4.023e-3	5.082e-3
Charcot-Marie-Tooth disease axonal type 2P	Hereditary motor and sensory neuropathies	0.01493	1	4.286e-3	5.381e-3
Hereditary motor and sensory neuropathies	X-linked hereditary motor and sensory neuropathy	0.01493	1	4.286e-3	5.381e-3
Charcot-Marie-Tooth disease type 2	Distal hereditary motor neuropathy	0.02632	1	4.671e-3	5.784e-3
Distal spinal muscular atrophy	multiple acyl-CoA dehydrogenase deficiency	0.02941	1	6.028e-3	7.265e-3
Charcot-marie-tooth disease	neuronopathy, distal hereditary motor, autosomal recessive 5	0.00752	1	8.573e-3	9.902e-3
Charcot-marie-tooth disease	X-linked hereditary motor and sensory neuropathy	0.00752	1	8.573e-3	9.902e-3
Amyotrophic lateral sclerosis	Telangiectasia–intellectual disability–microcephaly–metaphyseal dysplasia–eye abnormalities–short stature syndrome	0.00300	1	2.156e-2	2.338e-2