# GeDiPNet Cluster 128 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 14:17:46
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
peptide antigen assembly with MHC class I protein complex	GO:0002502	4	B2M, TAP1, TAP2, TAPBP	9	26	319.44	3.691e-10	9.157e-8
antigen processing and presentation of endogenous peptide antigen via MHC class I	GO:0019885	4	B2M, TAP1, TAP2, TAPBP	9	26	319.44	3.691e-10	9.157e-8
positive regulation of MHC class II biosynthetic process	GO:0045348	4	CIITA, RFX5, RFXANK, RFXAP	15	26	191.66	3.976e-9	7.613e-7
positive regulation of amyloid fibril formation	GO:1905908	3	APOE, APP, PSEN1	5	26	431.24	2.387e-8	3.637e-6
amyloid precursor protein metabolic process	GO:0042982	3	ACHE, APOE, PSEN1	12	26	179.68	5.217e-7	4.836e-5
cellular response to amyloid-beta	GO:1904646	4	APOE, APP, PSEN1, APOA1	53	26	54.24	8.230e-7	7.085e-5
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	GO:0002481	2	B2M, TAP2	2	26	718.73	1.861e-6	1.359e-4
cytosol to endoplasmic reticulum transport	GO:0046967	2	TAP1, TAP2	2	26	718.73	1.861e-6	1.359e-4
host-mediated suppression of symbiont invasion	GO:0046597	3	APCS, GSN, CIITA	24	26	89.84	4.746e-6	2.882e-4
regulation of amyloid-beta clearance	GO:1900221	2	APOE, APP	3	26	479.15	5.580e-6	3.275e-4
regulation of amyloid fibril formation	GO:1905906	2	APOE, APP	3	26	479.15	5.580e-6	3.275e-4
lipoprotein metabolic process	GO:0042157	3	APOE, APP, APOA1	26	26	82.93	6.086e-6	3.509e-4
amyloid fibril formation	GO:1990000	3	APP, GSN, B2M	29	26	74.35	8.529e-6	4.604e-4
positive regulation of phospholipid efflux	GO:1902995	2	APOE, APOA1	4	26	359.37	1.115e-5	5.663e-4
astrocyte activation involved in immune response	GO:0002265	2	APP, PSEN1	4	26	359.37	1.115e-5	5.663e-4
