# GeDiPNet Cluster 122 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 16:05:44
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
signal transduction	GO:0007165	78	AVP, CSF2, GNAI1, GNAI3, GRP, HRH3, NGF, POMC, TRH, ADORA1, CHRM2, CRH	2125	216	3.18	1.009e-21	2.035e-18
chemical synaptic transmission	GO:0007268	29	APP, HRH3, PDYN, TAC1, CHRM2, CRH, HTR1A, UTS2, CARTPT, GRIN1, GRIN2B, HTR2A	236	216	10.63	1.545e-21	2.997e-18
response to xenobiotic stimulus	GO:0009410	28	AVP, CRH, CYP1A1, DRD2, EDN1, DRD1, FYN, AHR, CASP3, CAT, TNF, COMT	248	216	9.77	8.136e-20	1.257e-16
vasodilation	GO:0042311	16	APOE, ADORA1, KNG1, CALCA, DRD1, INS, TNF, BDKRB2, GPER1, NOS1, ADORA2A, ACE	50	216	27.68	2.017e-19	2.863e-16
G protein-coupled receptor signaling pathway	GO:0007186	51	APOE, APP, GNAI1, GNAI3, HRH3, IL2, ADORA1, AGT, CHRM2, DRD2, EDN1, GCG	1031	216	4.28	3.829e-19	5.284e-16
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO:0007189	23	APP, AVP, GNAI1, GCG, GNAI2, HTR1A, CALCA, CNR1, CNR2, DRD1, PTHLH, VIP	161	216	12.36	9.019e-19	1.179e-15
response to ethanol	GO:0045471	20	AVP, IL2, CRH, DRD2, GNRH1, TACR1, FYN, TH, CASP8, CAT, TNF, DRD3	110	216	15.73	1.313e-18	1.673e-15
response to hypoxia	GO:0001666	23	ADORA1, CYP1A1, DRD2, EDN1, TH, CASP3, CASP9, CAT, TNF, AGER, COMT, ITGA2	176	216	11.31	6.977e-18	8.066e-15
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO:0007187	15	HRH3, CHRM2, HTR1A, CNR1, CNR2, DRD1, CCL2, HTR2A, MC1R, OPRM1, HTR2C, NPY	54	216	24.03	3.130e-17	3.113e-14
sensory perception of pain	GO:0019233	14	NGF, TAC1, AQP1, CCL2, HOXD1, MAPK3, MC1R, MECP2, OPRM1, PNOC, PROK2, SCN11A	44	216	27.53	4.210e-17	4.059e-14
regulation of blood pressure	GO:0008217	17	POMC, TAC1, AGT, EDN1, TACR1, UTS2, CALCA, PTGS2, COMT, PTGS1, NPY, ACE	83	216	17.72	6.471e-17	6.123e-14
negative regulation of blood pressure	GO:0045776	12	ADORA1, DRD2, CALCA, OXT, BDKRB1, DRD3, NOS1, NOS2, NPY, APLN, NPPA, UCN	28	216	37.08	1.082e-16	9.909e-14
positive regulation of MAPK cascade	GO:0043410	24	APP, IL6, ADORA1, EDN1, EDN3, DRD1, IL11, INS, MAP2K6, TNF, CARTPT, GPER1	224	216	9.27	1.360e-16	1.214e-13
neuropeptide signaling pathway	GO:0007218	18	GNAI1, GRP, PDYN, POMC, TAC1, NTS, CARTPT, CCKBR, GAL, OPRM1, PNOC, PROK2	111	216	14.03	6.139e-16	4.827e-13
positive regulation of cytosolic calcium ion concentration	GO:0007204	19	AVP, IL2, TAC1, EDN1, KNG1, TACR1, CALCA, OXT, BDKRB1, BDKRB2, CCKBR, GPER1	137	216	12.00	1.873e-15	1.354e-12