# GeDiPNet Cluster 121 -- Pairs Within Cluster -- generated 2026-10-07 21:07:07
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 17:17:47.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Cerebellar ataxia and hypogonadotropic hypogonadism	Cerebellar ataxia-hypogonadism	0.66667	2	8.436e-9	6.837e-8
Ataxia-hypogonadism-choroidal dystrophy syndrome	Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	0.50000	1	6.494e-5	2.317e-4
retinal dystrophy-ataxia-pituitary hormone abnormality-hypogonadism syndrome	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.50000	1	6.494e-5	2.317e-4
PNPLA6-related spastic paraplegia with or without ataxia	retinal dystrophy-ataxia-pituitary hormone abnormality-hypogonadism syndrome	0.50000	1	6.494e-5	2.317e-4
PNPLA6-related spastic paraplegia with or without ataxia	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.50000	1	6.494e-5	2.317e-4
Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	PNPLA6-related spastic paraplegia with or without ataxia	0.50000	1	6.494e-5	2.317e-4
Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	retinal dystrophy-ataxia-pituitary hormone abnormality-hypogonadism syndrome	0.50000	1	6.494e-5	2.317e-4
Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.50000	1	6.494e-5	2.317e-4
Boucher-neuhauser syndrome	PNPLA6-related spastic paraplegia with or without ataxia	0.50000	1	6.494e-5	2.317e-4
Boucher-neuhauser syndrome	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.50000	1	6.494e-5	2.317e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	Boucher-neuhauser syndrome	0.50000	1	6.494e-5	2.317e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.50000	1	6.494e-5	2.317e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	retinal dystrophy-ataxia-pituitary hormone abnormality-hypogonadism syndrome	0.50000	1	6.494e-5	2.317e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	PNPLA6-related spastic paraplegia with or without ataxia	0.50000	1	6.494e-5	2.317e-4
Boucher-neuhauser syndrome	Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	0.50000	1	6.494e-5	2.317e-4
Boucher-neuhauser syndrome	retinal dystrophy-ataxia-pituitary hormone abnormality-hypogonadism syndrome	0.50000	1	6.494e-5	2.317e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	Cerebellar ataxia-hypogonadism	0.33333	1	1.299e-4	3.908e-4
Boucher-neuhauser syndrome	Cerebellar ataxia-hypogonadism	0.33333	1	1.299e-4	3.908e-4
Cerebellar ataxia-hypogonadism	Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	0.33333	1	1.299e-4	3.908e-4
Cerebellar ataxia-hypogonadism	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.33333	1	1.299e-4	3.908e-4
Cerebellar ataxia and hypogonadotropic hypogonadism	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.33333	1	1.299e-4	3.908e-4
Cerebellar ataxia and hypogonadotropic hypogonadism	Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	0.33333	1	1.299e-4	3.908e-4
Boucher-neuhauser syndrome	Cerebellar ataxia and hypogonadotropic hypogonadism	0.33333	1	1.299e-4	3.908e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	Cerebellar ataxia and hypogonadotropic hypogonadism	0.33333	1	1.299e-4	3.908e-4
Beta-sarcoglycanopathy	Mucolipidosis	0.12500	1	4.546e-4	9.697e-4
GNPTG-mucolipidosis	Mucolipidosis	0.12500	1	4.546e-4	9.697e-4
Ataxia-hypogonadism-choroidal dystrophy syndrome	Mucolipidosis	0.12500	1	4.546e-4	9.697e-4
Boucher-neuhauser syndrome	Mucolipidosis	0.12500	1	4.546e-4	9.697e-4
Chorioretinal dystrophy, spinocerebellar ataxia, hypogonadotropic hypogonadism syndrome	Mucolipidosis	0.12500	1	4.546e-4	9.697e-4
Mucolipidosis	Trichomegaly-retina pigmentary degeneration-dwarfism syndrome	0.12500	1	4.546e-4	9.697e-4
Mucolipidosis	retinal dystrophy-ataxia-pituitary hormone abnormality-hypogonadism syndrome	0.12500	1	4.546e-4	9.697e-4