# GeDiPNet Cluster 12 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 00:36:40
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
skeletal system development	GO:0001501	38	FBN1, SMAD3, MMP9, TGFB2, TGFBR1, MMP14, NPR3, COL1A1, COL5A2, COL1A2, COL2A1, LTBP3	151	476	9.88	3.299e-27	1.339e-23
collagen fibril organization	GO:0030199	24	COL3A1, TGFB2, TGFBR1, LOX, COL1A1, COL5A1, COL5A2, TNXB, COL1A2, COL2A1, PLOD1, COL11A1	65	476	14.50	4.744e-22	9.978e-19
heart development	GO:0007507	34	CDKN1A, FBN1, COL3A1, TGFB2, TGFBR1, TGFBR2, SOD2, LOX, PRKG1, MMP2, PKD1, SMAD2	273	476	4.89	1.981e-14	1.193e-11
blood vessel remodeling	GO:0001974	14	AGT, TGFB2, NPR3, BGN, CBS, NPR2, ATP7A, JAG1, ACE, BMPR2, CHD7, IGF1	42	476	13.09	1.103e-12	4.936e-10
cartilage development	GO:0051216	18	COL3A1, TGFBR2, COL2A1, PKD1, NPR2, BMP7, COL11A1, COL11A2, COMP, FGFR3, IFT80, MATN3	89	476	7.94	8.482e-12	3.144e-9
positive regulation of epithelial to mesenchymal transition	GO:0010718	15	IL6, SMAD3, AGT, TGFB2, TGFBR1, TGFBR2, COL1A1, TNXB, SMAD2, TGFB3, BMP7, NOTCH1	59	476	9.98	1.414e-11	4.972e-9
elastic fiber assembly	GO:0048251	8	COL3A1, EFEMP2, MYH11, LOX, THSD4, TNXB, EMILIN1, ATP7A	11	476	28.55	2.580e-11	8.506e-9
extracellular matrix organization	GO:0030198	21	ADAMTS8, MMP1, MMP13, COL3A1, ELN, MMP9, TGFB2, MMP14, MMP2, TNXB, EMILIN1, MATN3	145	476	5.69	1.230e-10	3.437e-8
positive regulation of SMAD protein signal transduction	GO:0060391	12	GDF7, SMAD3, TGFB2, TGFBR1, TGFBR2, PARP1, TGFB3, BMP7, TGFBR3, SMAD4, BMPR2, BMP2	42	476	11.22	3.593e-10	8.772e-8
lung development	GO:0030324	17	FBN1, COL3A1, TGFBR2, MMP14, LOX, SMAD2, NOTCH1, ADAMTS2, COL6A1, ABCA3, TBX5, BMPR2	108	476	6.18	1.966e-9	3.988e-7
blood vessel development	GO:0001568	14	COL3A1, TGFB2, TGFBR2, LOX, COL1A1, COL5A1, COL1A2, PKD1, NPR2, ATP7A, HEY2, FOXO1	70	476	7.85	2.100e-9	4.213e-7
endochondral ossification	GO:0001958	10	MMP13, MMP14, COL1A1, COL2A1, CBS, NPR2, ALPL, FGFR3, IFT80, PEX7	31	476	12.66	2.873e-9	5.551e-7
regulation of cell population proliferation	GO:0042127	22	AGT, TGFB2, TGFBR2, ACE2, AGTR1, PTGS2, ABL1, EMILIN1, TGFB3, NOTCH1, SOX9, JAG1	201	476	4.30	9.917e-9	1.660e-6
skin development	GO:0043588	12	COL3A1, SLC2A10, COL1A1, COL5A1, COL5A2, PKD1, COMP, ADAMTS2, ATP7A, COL5A3, COL6A1, NGFR	55	476	8.57	1.055e-8	1.755e-6
bone mineralization	GO:0030282	12	MMP13, LOX, COL1A2, LTBP3, ALPL, COMP, EIF2AK3, FGFR3, PTH1R, SOX9, COL6A1, BMP2	56	476	8.41	1.313e-8	2.132e-6