# GeDiPNet Cluster 119 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 11:09:44
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
regulation of synaptic transmission, glutamatergic	GO:0051966	4	LRRK2, MEF2C, PSEN1, UNC13A	33	69	32.83	6.424e-6	3.665e-4
neuron cellular homeostasis	GO:0070050	4	CHMP2B, DCTN1, PSEN1, TMEM106B	33	69	32.83	6.424e-6	3.665e-4
maintenance of synapse structure	GO:0099558	3	DCTN1, GRN, CHCHD10	12	69	67.71	1.035e-5	5.352e-4
autophagy	GO:0006914	7	CHMP2B, LRRK2, OPTN, PSEN1, SQSTM1, VCP, C9orf72	221	69	8.58	1.704e-5	7.919e-4
locomotory exploration behavior	GO:0035641	3	APOE, GRN, LRRK2	16	69	50.78	2.607e-5	1.099e-3
astrocyte activation	GO:0048143	3	MAPT, PSEN1, TREM2	17	69	47.79	3.157e-5	1.270e-3
astrocyte activation involved in immune response	GO:0002265	2	GRN, PSEN1	4	69	135.41	8.024e-5	2.568e-3
cardiac muscle tissue regeneration	GO:0061026	2	ERBB4, GATA4	4	69	135.41	8.024e-5	2.568e-3
response to ischemia	GO:0002931	4	CSF1R, MEF2C, TREM2, SQSTM1	63	69	17.20	8.604e-5	2.705e-3
lysosome organization	GO:0007040	4	GRN, LRRK2, TMEM106B, WASHC5	65	69	16.67	9.725e-5	2.961e-3
synaptic transmission, cholinergic	GO:0007271	3	APOE, CHRNA4, CHRNB4	25	69	32.50	1.045e-4	3.123e-3
excitatory postsynaptic potential	GO:0060079	4	CHRNA4, CHRNB4, LRRK2, MEF2C	69	69	15.70	1.228e-4	3.526e-3
cellular response to lipoprotein particle stimulus	GO:0071402	2	APOE, TREM2	5	69	108.33	1.334e-4	3.754e-3
positive regulation of amyloid fibril formation	GO:1905908	2	APOE, PSEN1	5	69	108.33	1.334e-4	3.754e-3
microglial cell activation involved in immune response	GO:0002282	2	GRN, TREM2	5	69	108.33	1.334e-4	3.754e-3