# GeDiPNet Cluster 118 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 09:59:35
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
inflammatory response	GO:0006954	57	CCL2, CD14, CEBPB, CXCL10, FOS, IL18R1, IL1A, IL1B, IL1R1, IL1RN, IL6, LY86	467	265	8.61	7.426e-37	6.029e-33
response to lipopolysaccharide	GO:0032496	33	CEBPB, CXCL10, EPO, FOS, IL10, IL12RB2, IL1B, MPO, SOD2, TLR4, TNF, NOS2	161	265	14.45	6.224e-29	2.859e-25
immune response	GO:0006955	50	CCL2, CEBPB, CLEC4E, CSF3, CXCL10, IL10, IL18R1, IL1A, IL1B, IL1R1, IL1RN, IL2	543	265	6.49	1.776e-26	6.595e-23
negative regulation of apoptotic process	GO:0043066	49	BECN1, EPO, GSK3B, HSPA1A, IL10, IL2, IL31RA, IL6, IL7, JUN, MMP9, MPO	524	265	6.59	3.002e-26	1.081e-22
cellular response to lipopolysaccharide	GO:0071222	31	CCL2, CD14, CEBPB, CSF3, CXCL10, IL10, IL1A, IL1B, IL6, MMP9, TICAM2, TLR4	187	265	11.69	2.870e-24	8.350e-21
positive regulation of chemokine production	GO:0032722	19	IL1B, IL6, IL7, TLR2, TLR4, TLR9, TNF, EGR1, HIF1A, IL18, ADAM17, HMOX1	49	265	27.34	5.135e-23	1.263e-19
positive regulation of gene expression	GO:0010628	44	CCL2, CEBPB, FGF2, GSK3B, HSPA1A, IL1A, IL1B, IL6, IL7, PPP3CA, TLR2, TLR4	504	265	6.16	2.201e-22	4.926e-19
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	GO:0051897	31	BECN1, CSF3, FGF2, GSK3B, IL1B, IL1R1, NOX4, TNF, VEGFA, ITGB1, ANGPT1, CAT	217	265	10.07	2.931e-22	6.396e-19
apoptotic process	GO:0006915	52	BECN1, CD14, EPO, IL1A, IL1B, IRF1, JUN, MMP9, PARP1, TLR2, TNFRSF1A, TNFSF10	747	265	4.91	6.990e-22	1.427e-18
response to xenobiotic stimulus	GO:0009410	32	BECN1, ENO2, FOS, GABRB3, GABRG3, IL10, JUN, SOD2, TNF, RELA, ADD3, CASP3	248	265	9.10	1.463e-21	2.870e-18
positive regulation of inflammatory response	GO:0050729	24	CEBPB, IL1B, IL2, TLR2, TLR4, TLR9, TNF, TNFRSF1A, CCL3, IL17RA, IL18, MDK	122	265	13.87	7.530e-21	1.341e-17
positive regulation of ERK1 and ERK2 cascade	GO:0070374	28	CHRNA7, EPO, FGF2, IL1B, JUN, NOX4, TLR4, TNF, VEGFA, ICAM1, ANGPT1, CCL3	201	265	9.82	6.808e-20	1.066e-16
positive regulation of MAPK cascade	GO:0043410	29	CHRNA7, FGF2, IL1B, IL6, TLR9, TNF, VEGFA, NMNAT1, FGF1, IGF1, MAP2K1, SOD1	224	265	9.13	1.149e-19	1.708e-16
positive regulation of interleukin-6 production	GO:0032755	21	IL1A, IL1B, IL6, TLR1, TLR2, TLR4, TLR9, TNF, NOS2, RELA, IL17A, IL17RA	103	265	14.38	1.000e-18	1.303e-15
response to hypoxia	GO:0001666	25	BECN1, CHRNA7, EPO, SOD2, TNF, UCP2, VEGFA, NOS2, CASP3, CASP9, CAT, EGR1	176	265	10.02	4.406e-18	5.215e-15