# GeDiPNet Cluster 115 -- Enriched Pathways -- generated 2026-10-07 06:32:06
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
EPHB-mediated forward signaling	Reactome	3	ACTB, ACTG1, EFNB1	39	8	115.48	1.753e-6	7.871e-5
EPH-ephrin mediated repulsion of cells	Reactome	3	ACTB, ACTG1, EFNB1	50	8	90.08	3.747e-6	1.500e-4
Formation of annular gap junctions	Reactome	2	ACTB, ACTG1	11	8	272.95	2.129e-5	6.294e-4
Cell-extracellular matrix interactions	Reactome	2	ACTB, ACTG1	12	8	250.21	2.554e-5	7.280e-4
Gap junction degradation	Reactome	2	ACTB, ACTG1	12	8	250.21	2.554e-5	7.280e-4
Interaction between L1 and Ankyrins	Reactome	2	ACTB, ACTG1	13	8	230.96	3.017e-5	8.384e-4
Arginine biosynthesis	KEGG	2	ABHD14A-ACY1, ACY1	23	8	130.54	9.755e-5	2.205e-3
Hippo signaling pathway	KEGG	3	ACTB, ACTG1, BMP5	157	8	28.69	1.170e-4	2.541e-3
Adherens junctions interactions	Reactome	2	ACTB, ACTG1	32	8	93.83	1.907e-4	3.771e-3
RHO GTPases activate IQGAPs	Reactome	2	ACTB, ACTG1	32	8	93.83	1.907e-4	3.771e-3
2-Oxocarboxylic acid metabolism	KEGG	2	ABHD14A-ACY1, ACY1	33	8	90.98	2.029e-4	3.948e-3
RHO GTPases Activate WASPs and WAVEs	Reactome	2	ACTB, ACTG1	36	8	83.40	2.419e-4	4.535e-3
Signaling by high-kinase activity BRAF mutants	Reactome	2	ACTB, ACTG1	36	8	83.40	2.419e-4	4.535e-3
MAP2K and MAPK activation	Reactome	2	ACTB, ACTG1	40	8	75.06	2.990e-4	5.349e-3
Recycling pathway of L1	Reactome	2	ACTB, ACTG1	40	8	75.06	2.990e-4	5.349e-3