# GeDiPNet Cluster 114 -- Pairs Within Cluster -- generated 2026-10-07 02:56:38
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:00:13.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Combined saposin deficiency	Metachromatic leukodystrophy	0.22222	2	2.362e-7	1.638e-6
Combined saposin deficiency	Gaucher disease	0.11111	2	1.147e-6	7.037e-6
Gaucher disease	Hereditary parkinson disease	0.06977	3	3.600e-6	2.027e-5
Gaucher disease	Metachromatic leukodystrophy	0.08333	2	3.200e-5	1.564e-4
Combined psap deficiency	metachromatic leukodystrophy due to saposin B deficiency	0.50000	1	6.494e-5	2.342e-4
Krabbe disease due to saposin A deficiency	metachromatic leukodystrophy due to saposin B deficiency	0.50000	1	6.494e-5	2.342e-4
Gaucher disease due to saposin C deficiency	Krabbe disease due to saposin A deficiency	0.50000	1	6.494e-5	2.342e-4
Gaucher disease due to saposin C deficiency	metachromatic leukodystrophy due to saposin B deficiency	0.50000	1	6.494e-5	2.342e-4
Combined psap deficiency	Krabbe disease due to saposin A deficiency	0.50000	1	6.494e-5	2.342e-4
Combined psap deficiency	Gaucher disease due to saposin C deficiency	0.50000	1	6.494e-5	2.342e-4
Combined saposin deficiency	Krabbe disease due to saposin A deficiency	0.33333	1	1.299e-4	3.898e-4
Combined saposin deficiency	Gaucher disease due to saposin C deficiency	0.33333	1	1.299e-4	3.898e-4
Combined saposin deficiency	metachromatic leukodystrophy due to saposin B deficiency	0.33333	1	1.299e-4	3.898e-4
Combined psap deficiency	Combined saposin deficiency	0.33333	1	1.299e-4	3.898e-4
Combined psap deficiency	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.041e-3
Gaucher disease due to saposin C deficiency	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.041e-3
Krabbe disease due to saposin A deficiency	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.041e-3
Alexander disease	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.041e-3
Metachromatic leukodystrophy	metachromatic leukodystrophy due to saposin B deficiency	0.11111	1	5.195e-4	1.041e-3
Metachromatic leukodystrophy	mucopolysaccharidosis type 6	0.11111	1	5.195e-4	1.041e-3
Gaucher disease	Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome	0.05556	1	1.104e-3	1.805e-3
Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome	Hereditary parkinson disease	0.03448	1	1.818e-3	2.662e-3