# GeDiPNet Cluster 114 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 13:48:25
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
adult locomotory behavior	GO:0008344	6	CLN8, SNCA, GIGYF2, NR4A2, PARK7, PRKN	56	48	41.71	6.122e-9	1.117e-6
regulation of reactive oxygen species metabolic process	GO:2000377	5	SNCA, TNF, LRRK2, PINK1, PRKN	27	48	72.09	6.982e-9	1.253e-6
regulation of synaptic vesicle transport	GO:1902803	3	LRRK2, PINK1, PRKN	3	48	389.31	1.591e-8	2.556e-6
mitochondrion to lysosome vesicle-mediated transport	GO:0099074	3	VPS35, PINK1, PRKN	3	48	389.31	1.591e-8	2.556e-6
dopamine metabolic process	GO:0042417	4	SNCA, NR4A2, PRKN, SNCAIP	18	48	86.51	1.142e-7	1.347e-5
negative regulation of mitochondrial fission	GO:0090258	3	MAPT, PINK1, PRKN	5	48	233.59	1.585e-7	1.781e-5
positive regulation of protein localization to cell periphery	GO:1904377	3	SNCA, VPS35, EIF4G1	5	48	233.59	1.585e-7	1.781e-5
negative regulation of neuron apoptotic process	GO:0043524	7	CLN8, SNCA, FGF20, NR4A2, PARK7, PINK1, PRKN	160	48	17.03	1.622e-7	1.816e-5
dopamine uptake involved in synaptic transmission	GO:0051583	3	SNCA, PARK7, PRKN	6	48	194.66	3.164e-7	3.180e-5
cellular response to oxidative stress	GO:0034599	6	SNCA, LRRK2, NR4A2, PARK7, PINK1, PRKN	111	48	21.04	3.840e-7	3.744e-5
regulation of presynapse assembly	GO:1905606	4	NTRK3, SNCA, VPS35, EIF4G1	29	48	53.70	8.680e-7	7.394e-5
cellular response to toxic substance	GO:0097237	3	TNF, PINK1, PRKN	12	48	97.33	3.443e-6	2.230e-4
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	GO:1903377	3	PARK7, PINK1, PRKN	14	48	83.42	5.676e-6	3.317e-4
negative regulation of late endosome to lysosome transport	GO:1902823	2	LRRK2, VPS35	2	48	389.31	6.461e-6	3.680e-4
positive regulation of dopamine biosynthetic process	GO:1903181	2	VPS35, PARK7	2	48	389.31	6.461e-6	3.680e-4
