# GeDiPNet Cluster 112 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 13:39:08
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
heart development	GO:0007507	70	DYNC2H1, ECE1, EDN1, EDNRA, GATA4, GNA11, HAND2, ISL1, MAPK1, MKKS, NIPBL, NKX2-5	273	456	10.51	1.430e-51	3.328e-47
positive regulation of transcription by RNA polymerase II	GO:0045944	121	ABL1, AHR, CBFB, CDK13, CDK8, EDN1, ETV2, EYA1, GATA4, GATA6, HAND2, HIF1A	1208	456	4.10	9.361e-43	1.210e-38
positive regulation of DNA-templated transcription	GO:0045893	85	AHR, EYA1, GATA4, GATA6, HAND2, HIF1A, KLF4, MYRF, NFATC1, NKX2-5, NOTCH1, PITX2	778	456	4.48	3.143e-32	1.892e-28
negative regulation of transcription by RNA polymerase II	GO:0000122	96	CBFB, EDN1, FOXP1, GATA4, GATA6, GSTP1, IRX1, ISL1, KLF4, NIPBL, NKX2-5, NOTCH1	1002	456	3.93	7.325e-32	4.262e-28
skeletal system development	GO:0001501	41	COL11A2, COL2A1, EDN1, GDF3, GNA11, TGFB2, TLL1, UFD1, ZIC3, BMP7, CHRD, COL1A1	151	456	11.13	1.808e-31	1.002e-27
outflow tract morphogenesis	GO:0003151	29	EYA1, HAND2, HIF1A, ISL1, NIPBL, NKX2-5, NOTCH1, PITX2, TBX1, TBX20, TGFB2, VEGFA	63	456	18.86	2.511e-30	1.235e-26
regulation of transcription by RNA polymerase II	GO:0006357	113	AHR, CBFB, ETV2, FOXP1, GATA4, GATA6, HAND2, HIF1A, HOXA1, HOXA3, IRX1, IRX5	1602	456	2.89	8.299e-26	2.786e-22
regulation of DNA-templated transcription	GO:0006355	106	ABL1, AHR, ETV2, FOXP1, GATA4, GATA6, HAND2, HIF1A, HOXA1, HOXA3, IRX1, IRX5	1454	456	2.99	2.959e-25	9.306e-22
outflow tract septum morphogenesis	GO:0003148	19	GATA6, ISL1, NKX2-5, ROBO1, SMAD6, TBX1, TBX20, TGFB2, BMPR1A, ACVR1, BMPR2, FGF8	28	456	27.81	8.940e-25	2.645e-21
heart morphogenesis	GO:0003007	25	COL2A1, HAND2, ISL1, NIPBL, NKX2-5, TBX1, TGFB2, VEGFA, BMPR1A, DLC1, DCHS1, FGF8	61	456	16.80	9.880e-25	2.898e-21
cell differentiation	GO:0030154	86	CAV3, ETV2, EYA1, GATA4, GATA6, HAND2, HIF1A, ISL1, MYRF, NKX2-5, NOTCH1, PRKD1	1051	456	3.35	1.178e-23	3.212e-20
lung development	GO:0030324	30	NOTCH1, PITX2, STRA6, TBX5, VEGFA, BMPR1A, FGF10, ZIC3, SMAD2, BMPR2, FGF8, FOXP2	108	456	11.38	1.248e-23	3.350e-20
roof of mouth development	GO:0060021	24	COL11A2, COL2A1, HAND2, WDPCP, BMPR1A, OSR1, PDGFRA, SNAI1, TCF21, ALX1, ALX4, BNC2	70	456	14.05	1.359e-21	2.695e-18
positive regulation of gene expression	GO:0010628	55	ETV2, HAND2, HIF1A, IRX1, KLF4, NKX2-5, NOTCH1, PRKD1, ROBO1, TGFB2, VEGFA, BMPR1A	504	456	4.47	7.267e-21	1.301e-17
ventricular septum morphogenesis	GO:0060412	19	ADAMTS19, NKX2-5, NOTCH1, PITX2, ROBO1, TGFB2, BMPR1A, CITED2, ACVR1, BMPR2, GJA5, HEY1	41	456	18.99	2.364e-20	3.987e-17