# GeDiPNet Cluster 111 -- Pairs Within Cluster -- generated 2026-10-08 04:54:51
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:00:13.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Cyclin-dependent kinase-like 5 deficiency	Rett syndrome	0.15000	3	1.838e-8	1.444e-7
Bruxism	Cyclin-dependent kinase-like 5 deficiency	0.25000	2	3.795e-7	2.400e-6
Angelman syndrome	Bruxism	0.16667	2	1.138e-6	6.639e-6
Cyclin-dependent kinase-like 5 deficiency	Retinoschisis	0.20000	2	1.265e-6	7.314e-6
Bruxism	Rett syndrome	0.11111	2	3.035e-6	1.636e-5
Angelman syndrome	Cyclin-dependent kinase-like 5 deficiency	0.13333	2	5.686e-6	2.931e-5
Retinoschisis	Rett syndrome	0.10000	2	1.010e-5	5.015e-5
Angelman syndrome	Rett syndrome	0.08000	2	4.533e-5	2.064e-4
Congenital retinal aneurysm	Congenital retinal anomaly	0.50000	1	6.494e-5	2.317e-4
Congenital retinal aneurysm	X-linked retinoschisis	0.50000	1	6.494e-5	2.317e-4
Congenital retinal anomaly	X-linked retinoschisis	0.50000	1	6.494e-5	2.317e-4
Bruxism	CDKL5 disorder	0.25000	1	1.948e-4	5.325e-4
Congenital retinal aneurysm	Retinoschisis	0.16667	1	3.247e-4	7.680e-4
Congenital retinal anomaly	Retinoschisis	0.16667	1	3.247e-4	7.680e-4
Retinoschisis	X-linked retinoschisis	0.16667	1	3.247e-4	7.680e-4
CDKL5 disorder	Retinoschisis	0.16667	1	3.247e-4	7.680e-4
Congenital retinal aneurysm	Cyclin-dependent kinase-like 5 deficiency	0.14286	1	3.897e-4	8.637e-4
Cyclin-dependent kinase-like 5 deficiency	X-linked retinoschisis	0.14286	1	3.897e-4	8.637e-4
Congenital retinal anomaly	Cyclin-dependent kinase-like 5 deficiency	0.14286	1	3.897e-4	8.637e-4
CDKL5 disorder	Cyclin-dependent kinase-like 5 deficiency	0.14286	1	3.897e-4	8.637e-4
Angelman syndrome	CDKL5 disorder	0.09091	1	6.494e-4	1.239e-3
Angelman syndrome	Childhood-onset autosomal recessive slowly progressive spinocerebellar ataxia	0.09091	1	6.494e-4	1.239e-3
Rett syndrome	X-linked retinoschisis	0.05882	1	1.039e-3	1.737e-3
Congenital retinal anomaly	Rett syndrome	0.05882	1	1.039e-3	1.737e-3
Congenital retinal aneurysm	Rett syndrome	0.05882	1	1.039e-3	1.737e-3
CDKL5 disorder	Rett syndrome	0.05882	1	1.039e-3	1.737e-3