# GeDiPNet Cluster 11 -- Pairs Within Cluster -- generated 2026-10-07 15:10:43
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 17:17:47.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Male infertility single gene azoospermia	Spermatogenic failure	0.20652	38	1.042e-55	5.956e-54
Congenital impairment of spermatozoa motility	Spermatogenic failure	0.16949	20	7.341e-41	3.140e-39
Male infertility single gene azoospermia	Testicular azoospermia	0.16529	20	5.607e-36	2.117e-34
Spermatogenic failure	Testicular azoospermia	0.15625	20	2.241e-35	8.181e-34
Azoospermia	Male infertility single gene azoospermia	0.10236	13	1.292e-20	2.547e-19
Azoospermia	Spermatogenic failure	0.09701	13	3.066e-20	5.944e-19
Male infertility	Spermatogenic failure	0.08654	18	1.498e-19	2.784e-18
Azoospermia	Premature ovarian failure	0.07299	10	1.862e-14	2.563e-13
Male infertility	Testicular azoospermia	0.07407	10	2.019e-14	2.775e-13
Male infertility	Male infertility single gene azoospermia	0.06829	14	3.072e-14	4.148e-13
Premature ovarian failure	Spermatogenic failure	0.06512	14	1.106e-13	1.431e-12
Azoospermia	Testicular azoospermia	0.11864	7	3.408e-13	4.317e-12
Congenital impairment of spermatozoa motility	Teratozoospermia	0.13333	6	1.584e-12	1.895e-11
Male infertility single gene azoospermia	Premature ovarian failure	0.05213	11	3.832e-10	3.632e-9
Spermatogenic failure	Teratozoospermia	0.05185	7	7.954e-10	7.294e-9
Azoospermia	Male infertility	0.04348	6	9.527e-8	6.696e-7
Congenital impairment of spermatozoa motility	primary ciliary dyskinesia	0.10000	3	2.431e-7	1.600e-6
primary ciliary dyskinesia	Teratozoospermia	0.08824	3	4.011e-7	2.529e-6
Congenital impairment of spermatozoa motility	Male infertility spermatogenesis disorder	0.08108	3	1.610e-6	9.162e-6
Male infertility large polyploid spermatozoa	Male infertility spermatogenesis disorder	0.08333	2	3.629e-5	1.670e-4
Congenital impairment of spermatozoa motility	Spermatogenic failure, x-linked	0.06667	2	5.943e-5	2.317e-4
Male infertility teratozoospermia	Spermatogenic failure	0.01739	2	5.434e-5	2.317e-4
Spermatogenic failure, x-linked	Testicular azoospermia	0.05000	2	1.237e-4	3.908e-4
primary ciliary dyskinesia	spermatogenic failure 18	0.10000	1	5.845e-4	1.154e-3
primary ciliary dyskinesia	Young syndrome	0.10000	1	5.845e-4	1.154e-3
primary ciliary dyskinesia	spermatogenic failure 56	0.10000	1	5.845e-4	1.154e-3
Male infertility large polyploid spermatozoa	spermatogenic failure 5	0.10000	1	5.845e-4	1.154e-3
Male infertility large polyploid spermatozoa	spermatogenic failure 46	0.10000	1	5.845e-4	1.154e-3
Male infertility large polyploid spermatozoa	spermatogenic failure 56	0.10000	1	5.845e-4	1.154e-3
Male infertility spermatogenesis disorder	spermatogenic failure 38	0.05882	1	1.039e-3	1.737e-3
Male infertility spermatogenesis disorder	spermatogenic failure 39	0.05882	1	1.039e-3	1.737e-3
Male infertility spermatogenesis disorder	spermatogenic failure 5	0.05882	1	1.039e-3	1.737e-3
Congenital impairment of spermatozoa motility	spermatogenic failure 18	0.04167	1	1.494e-3	2.311e-3
Congenital impairment of spermatozoa motility	spermatogenic failure 38	0.04167	1	1.494e-3	2.311e-3
Congenital impairment of spermatozoa motility	spermatogenic failure 39	0.04167	1	1.494e-3	2.311e-3
Spermatogenic failure, x-linked	Synovial sarcoma	0.09091	1	1.558e-3	2.374e-3
Teratozoospermia	X-linked intellectual disability, Cabezas type	0.03571	1	1.753e-3	2.607e-3
ciliary dyskinesia, primary, 45	Teratozoospermia	0.03571	1	1.753e-3	2.607e-3
spermatogenic failure 56	Teratozoospermia	0.03571	1	1.753e-3	2.607e-3
spermatogenic failure 38	Teratozoospermia	0.03571	1	1.753e-3	2.607e-3
spermatogenic failure 18	Teratozoospermia	0.03571	1	1.753e-3	2.607e-3
Ruijs-aalfs syndrome	Teratozoospermia	0.03571	1	1.753e-3	2.607e-3
Congenital impairment of spermatozoa motility	Male infertility teratozoospermia	0.04000	1	2.985e-3	3.948e-3
Congenital impairment of spermatozoa motility	Synovial sarcoma	0.03846	1	4.475e-3	5.601e-3
Male infertility large polyploid spermatozoa	Spermatogenic failure, x-linked	0.05882	1	4.667e-3	5.786e-3
Male infertility single gene azoospermia	spermatogenic failure 56	0.00926	1	6.949e-3	8.230e-3
Male infertility single gene azoospermia	SYCE1-related gametogenic failure	0.00926	1	6.949e-3	8.230e-3
Male infertility	spermatogenic failure 5	0.00893	1	7.209e-3	8.515e-3
Spermatogenic failure	spermatogenic failure 46	0.00870	1	7.404e-3	8.700e-3
Spermatogenic failure	spermatogenic failure 39	0.00870	1	7.404e-3	8.700e-3
Spermatogenic failure	spermatogenic failure 5	0.00870	1	7.404e-3	8.700e-3
Spermatogenic failure	spermatogenic failure 38	0.00870	1	7.404e-3	8.700e-3
Premature ovarian failure	SYCE1-related gametogenic failure	0.00870	1	7.404e-3	8.700e-3
Spermatogenic failure	SYCE1-related gametogenic failure	0.00870	1	7.404e-3	8.700e-3
Congenital alpha-fetoprotein deficiency	Premature ovarian failure	0.00870	1	7.404e-3	8.700e-3