# GeDiPNet Cluster 108 -- Enriched Pathways -- generated 2026-10-08 13:15:04
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Regulation of Complement cascade	Reactome	3	CFH, CFI, CD46	47	19	40.35	5.209e-5	1.340e-3
Complement and coagulation cascades	KEGG	3	CFH, CFI, CD46	88	19	21.55	3.384e-4	5.992e-3
Staphylococcus aureus infection	KEGG	3	CFH, IL10, CFI	99	19	19.15	4.784e-4	7.880e-3
Negative regulation of NOTCH4 signaling	Reactome	1	NOTCH4	2	19	316.05	3.162e-3	3.236e-2
NOTCH4 Activation and Transmission of Signal to the Nucleus	Reactome	1	NOTCH4	2	19	316.05	3.162e-3	3.236e-2
Inflammatory bowel disease	KEGG	2	IL10, RORA	66	19	19.15	4.789e-3	4.325e-2
Virion - Adenovirus	KEGG	1	CD46	4	19	158.03	6.314e-3	5.220e-2
STING mediated induction of host immune responses	Reactome	1	DDX41	5	19	126.42	7.886e-3	6.037e-2
Defective LFNG causes SCDO3	Reactome	1	NOTCH4	5	19	126.42	7.886e-3	6.037e-2
Pre-NOTCH Processing in Golgi	Reactome	1	NOTCH4	6	19	105.35	9.457e-3	6.764e-2
Interleukin-4 and Interleukin-13 signaling	Reactome	2	IL10, RORA	108	19	11.71	1.240e-2	7.999e-2
CD163 mediating an anti-inflammatory response	Reactome	1	IL10	9	19	70.23	1.415e-2	8.635e-2
Tryptophan catabolism	Reactome	1	SLC7A5	11	19	57.46	1.727e-2	9.767e-2
Virion - Ebolavirus, Lyssavirus and Morbillivirus	KEGG	1	CD46	12	19	52.68	1.883e-2	1.026e-1
IRF3-mediated induction of type I IFN	Reactome	1	DDX41	13	19	48.62	2.038e-2	1.069e-1