# GeDiPNet Cluster 107 -- Enriched Pathways -- generated 2026-10-08 10:55:51
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Cobalamin (Cbl, vitamin B12) transport and metabolism	Reactome	8	AMN, CUBN, TCN1, TCN2, CD320, MMAA, MMUT, ABCD4	21	37	123.66	7.133e-16	2.561e-13
Cobalamin transport and metabolism	KEGG	6	TCN1, TCN2, CD320, MMAA, MMUT, ABCD4	18	37	108.20	1.010e-11	1.726e-9
Vitamin digestion and absorption	KEGG	6	AMN, CUBN, SLC19A2, TCN2, SLC19A1, ABCD4	26	37	74.91	1.230e-10	1.654e-8
Glycosphingolipid biosynthesis - lacto and neolacto series	KEGG	4	FUT1, FUT2, FUT3, FUT6	28	37	46.37	1.480e-6	6.853e-5
Vitamin D (calciferol) metabolism	Reactome	3	CUBN, CYP2R1, GC	11	37	88.53	4.367e-6	1.730e-4
Defective MMAA causes methylmalonic aciduria type cblA	Reactome	2	MMAA, MMUT	2	37	324.59	9.235e-6	3.209e-4
Defective MUT causes methylmalonic aciduria mut type	Reactome	2	MMAA, MMUT	2	37	324.59	9.235e-6	3.209e-4
Defective CD320 causes methylmalonic aciduria	Reactome	2	TCN2, CD320	2	37	324.59	9.235e-6	3.209e-4
Metabolism of folate and pterines	Reactome	3	DHFR, MTHFR, SLC19A1	17	37	57.28	1.777e-5	5.513e-4
Lewis blood group biosynthesis	Reactome	3	FUT2, FUT3, FUT6	18	37	54.10	2.128e-5	6.428e-4
ABO blood group biosynthesis	Reactome	2	FUT1, FUT2	3	37	216.40	2.765e-5	7.947e-4
Defective AMN causes hereditary megaloblastic anemia 1	Reactome	2	AMN, CUBN	3	37	216.40	2.765e-5	7.947e-4
Defective CUBN causes hereditary megaloblastic anemia 1	Reactome	2	AMN, CUBN	3	37	216.40	2.765e-5	7.947e-4
Propionyl-CoA catabolism	Reactome	2	MMAA, MMUT	5	37	129.84	9.182e-5	2.118e-3
HDL clearance	Reactome	2	AMN, CUBN	5	37	129.84	9.182e-5	2.118e-3