# GeDiPNet Cluster 105 -- Enriched Pathways -- generated 2026-10-08 20:21:28
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Threonine catabolism	Reactome	1	RIDA	4	26	115.48	8.632e-3	6.396e-2
HHAT G278V abrogates palmitoylation of Hh-Np	Reactome	1	SHH	4	26	115.48	8.632e-3	6.396e-2
Collagen biosynthesis and modifying enzymes	Reactome	2	COL4A1, ADAMTS14	67	26	13.79	9.140e-3	6.622e-2
Glycerophospholipid biosynthesis	Reactome	1	AGK	5	26	92.38	1.078e-2	7.350e-2
Release of Hh-Np from the secreting cell	Reactome	1	SHH	7	26	65.99	1.506e-2	8.969e-2
Ligand-receptor interactions	Reactome	1	SHH	7	26	65.99	1.506e-2	8.969e-2
Advanced glycosylation endproduct receptor signaling	Reactome	1	AGER	8	26	57.74	1.719e-2	9.741e-2
AGE-RAGE signaling pathway in diabetic complications	KEGG	2	COL4A1, AGER	101	26	9.15	1.996e-2	1.057e-1
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	Reactome	1	SEMA3A	10	26	46.19	2.145e-2	1.104e-1
Interaction between L1 and Ankyrins	Reactome	1	ANK3	13	26	35.53	2.779e-2	1.275e-1
Sema3A PAK dependent Axon repulsion	Reactome	1	SEMA3A	15	26	30.79	3.200e-2	1.375e-1
Extracellular matrix organization	Reactome	1	COL4A1	15	26	30.79	3.200e-2	1.375e-1
Anchoring fibril formation	Reactome	1	COL4A1	15	26	30.79	3.200e-2	1.375e-1
CRMPs in Sema3A signaling	Reactome	1	SEMA3A	16	26	28.87	3.410e-2	1.421e-1
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Reactome	1	PRNP	16	26	28.87	3.410e-2	1.421e-1