# GeDiPNet Cluster 104 -- Top Shared Genes -- generated 2026-10-08 09:05:50
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-08 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
STAT4	5	11	Crest syndrome; Dermatomyositis; Diffuse cutaneous systemic sclerosis; Scleroderma; Systemic scleroderma
HLA-DPA1	4	11	Dermatomyositis; Diffuse cutaneous systemic sclerosis; Irritant dermatitis; Systemic scleroderma
HLA-DPB1	4	11	Dermatomyositis; Diffuse cutaneous systemic sclerosis; Irritant dermatitis; Systemic scleroderma
IRF5	4	11	Crest syndrome; Diffuse cutaneous systemic sclerosis; Scleroderma; Systemic scleroderma
TGFBR1	4	11	Dermatomyositis; Diffuse cutaneous systemic sclerosis; multiple self-healing squamous epithelioma; Scleroderma
CAV1	3	11	Crest syndrome; Diffuse cutaneous systemic sclerosis; Scleroderma
CCN2	3	11	Crest syndrome; Diffuse cutaneous systemic sclerosis; Scleroderma
HLA-DRB5	3	11	Crest syndrome; Dermatomyositis; Systemic scleroderma
TNPO3	3	11	Crest syndrome; Diffuse cutaneous systemic sclerosis; Systemic scleroderma
ATG5	2	11	Crest syndrome; spinocerebellar ataxia, autosomal recessive 25
C2	2	11	Dermatomyositis; Irritant dermatitis
CCR6	2	11	Crest syndrome; Diffuse cutaneous systemic sclerosis
CD247	2	11	immunodeficiency 25; Scleroderma
DNASE1L3	2	11	autosomal systemic lupus erythematosus type 16; Crest syndrome
FCGR2B	2	11	Crest syndrome; Systemic scleroderma
FCGR3B	2	11	Crest syndrome; Systemic scleroderma
HLA-DRB1	2	11	Crest syndrome; Diffuse cutaneous systemic sclerosis
TAP2	2	11	Diffuse cutaneous systemic sclerosis; Scleroderma
TNF	2	11	Dermatomyositis; Scleroderma
TTC8	2	11	Crest syndrome; TTC8-related ciliopathy