# GeDiPNet Cluster 100 -- Pairs Within Cluster -- generated 2026-10-09 00:37:33
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:00:13.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Combined saposin deficiency	Metachromatic leukodystrophy	0.22222	2	2.362e-7	1.552e-6
Combined saposin deficiency	Retinitis pigmentosa-deafness syndrome	0.16667	2	4.640e-7	2.897e-6
Combined saposin deficiency	Gaucher disease	0.11111	2	1.147e-6	6.664e-6
Gaucher disease	Hereditary parkinson disease	0.06977	3	3.600e-6	1.918e-5
Metachromatic leukodystrophy	Retinitis pigmentosa-deafness syndrome	0.11111	2	1.296e-5	6.320e-5
Gaucher disease	Metachromatic leukodystrophy	0.08333	2	3.200e-5	1.479e-4
Combined psap deficiency	Gaucher disease due to saposin C deficiency	0.50000	1	6.494e-5	2.329e-4
Gaucher disease due to saposin C deficiency	Krabbe disease due to saposin A deficiency	0.50000	1	6.494e-5	2.329e-4
Combined psap deficiency	Krabbe disease due to saposin A deficiency	0.50000	1	6.494e-5	2.329e-4
Gaucher disease	Retinitis pigmentosa-deafness syndrome	0.07407	2	6.273e-5	2.329e-4
Combined saposin deficiency	Krabbe disease due to saposin A deficiency	0.33333	1	1.299e-4	3.929e-4
Combined saposin deficiency	Gaucher disease due to saposin C deficiency	0.33333	1	1.299e-4	3.929e-4
Combined psap deficiency	Combined saposin deficiency	0.33333	1	1.299e-4	3.929e-4
Combined psap deficiency	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.060e-3
Gaucher disease due to saposin C deficiency	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.060e-3
Krabbe disease due to saposin A deficiency	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.060e-3
Metachromatic leukodystrophy	mucopolysaccharidosis type 6	0.11111	1	5.195e-4	1.060e-3
Alexander disease	Metachromatic leukodystrophy	0.11111	1	5.195e-4	1.060e-3
Combined psap deficiency	Retinitis pigmentosa-deafness syndrome	0.08333	1	7.144e-4	1.335e-3
Gaucher disease due to saposin C deficiency	Retinitis pigmentosa-deafness syndrome	0.08333	1	7.144e-4	1.335e-3
Krabbe disease due to saposin A deficiency	Retinitis pigmentosa-deafness syndrome	0.08333	1	7.144e-4	1.335e-3
Gaucher disease	Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome	0.05556	1	1.104e-3	1.826e-3
Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome	Hereditary parkinson disease	0.03448	1	1.818e-3	2.676e-3