# GeDiPNet Cluster 100 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 00:37:52
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
positive regulation of gene expression	GO:0010628	23	CDKN2A, DNMT1, HES1, HSPA1A, HSPA1B, KRAS, NFE2L2, NOTCH1, RELA, VEGFA, MAPK14, NOS3	504	117	7.29	6.666e-14	3.700e-11
Notch signaling pathway	GO:0007219	13	DTX1, DTX4, HES1, HEY1, HEY2, JAG1, JAG2, NOTCH1, NOTCH3, NOTCH4, TGFB1, NR1H4	117	117	17.75	4.121e-13	1.993e-10
aortic valve morphogenesis	GO:0003180	9	HEY1, HEY2, JAG1, NOTCH1, NOS3, TGFB1, ADAMTS5, NPPA, SNAI1	37	117	38.85	1.162e-12	5.153e-10
negative regulation of gene expression	GO:0010629	18	DNMT1, HES1, HEY2, MAP3K7, NOTCH1, VEGFA, SIRT1, NOS2, TGFB1, AKT1, GPER1, IFNA2	339	117	8.48	3.769e-12	1.519e-9
response to hypoxia	GO:0001666	14	MAP3K7, VEGFA, CYGB, NOS2, TGFB1, CYBA, CYP1A1, LEP, PPARA, EDN1, NPPA, NPPC	176	117	12.70	5.081e-12	1.989e-9
pulmonary valve morphogenesis	GO:0003184	7	HEY1, HEY2, JAG1, NOTCH1, NOS3, ADAMTS5, TGFB2	18	117	62.11	9.455e-12	3.449e-9
cellular response to tumor necrosis factor	GO:0071356	11	HES1, MAP3K7, NFE2L2, RELA, SIRT1, MAPK14, AKT1, CYBA, GPER1, CCL2, EDN1	107	117	16.42	6.720e-11	1.983e-8
negative regulation of transcription by RNA polymerase II	GO:0000122	27	CDKN2A, DNMT1, HES1, HEY1, HEY2, HSPA1A, NOTCH1, NOTCH3, NOTCH4, RELA, VEGFA, YEATS2	1002	117	4.30	8.278e-11	2.394e-8
positive regulation of transcription by RNA polymerase II	GO:0045944	29	CDKN2A, HES1, HEY1, HEY2, JAG1, NFE2L2, NOTCH1, NOTCH3, NOTCH4, OSM, RELA, VEGFA	1208	117	3.83	2.218e-10	5.749e-8
regulation of cell population proliferation	GO:0042127	13	AGTR1, CXCL11, DNMT1, JAG1, JAG2, NOTCH1, SIRT1, NOS2, TGFB1, NR5A2, AGT, MMP7	201	117	10.33	4.062e-10	9.746e-8
negative regulation of biomineral tissue development	GO:0070168	5	HEY1, HEY2, NOTCH1, NOS3, TGFB1	10	117	79.86	2.170e-9	4.336e-7
negative regulation of cell growth	GO:0030308	10	CDKN2A, HSPA1A, HSPA1B, STK11, TGFB1, SESN2, NPPA, NPPB, SMAD3, TGFB2	115	117	13.89	2.691e-9	5.244e-7
blood vessel diameter maintenance	GO:0097746	7	AGTR1, NOS3, AGT, EDN1, NPPA, NPPB, NPPC	37	117	30.22	2.773e-9	5.372e-7
angiogenesis	GO:0001525	14	HEY1, JAG1, NOTCH1, VEGFA, SIRT1, MAPK14, NOS3, CYP1B1, LEP, LEPR, CCL2, FN1	284	117	7.87	2.890e-9	5.568e-7
intracellular receptor signaling pathway	GO:0030522	7	AHR, NR1H2, NR1H4, NR1I2, NR1I3, NR5A2, PPARA	39	117	28.67	4.100e-9	7.622e-7