WASL (WASP like actin nucleation promoting factor)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8976 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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WASP like actin nucleation promoting factor |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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WASL |
Synonyms (NCBI Gene)
Gene synonyms aliases
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N-WASP, NWASP, WASPB |
Chromosome
Chromosome number
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7 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7q31.32 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | O00401 | |||||||||||||||||||||||||
Protein name | Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP) | |||||||||||||||||||||||||
Protein function | Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex (PubMed:16767080, PubMed:19366662, PubMed:19487689, PubMed:22847007, PubMed:22921828, PubMed:9422512). Involved in various processes, such as mitos | |||||||||||||||||||||||||
PDB | 2FF3 , 2LNH , 2VCP , 4CC2 , 4CC7 , 9DLX | |||||||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 505 | |||||||||||||||||||||||||
Interactions | View interactions |