WASF2 (WASP family member 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
10163 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
WASP family member 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
WASF2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
SCAR2 |
Chromosome
Chromosome number
|
1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1p36.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all |
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Transcription factors | |||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | |||||||||||
UniProt ID | Q9Y6W5 | ||||||||||
Protein name | Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2) | ||||||||||
Protein function | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formatio | ||||||||||
PDB | 2A40 | ||||||||||
Family and domains |
Pfam
|
||||||||||
Tissue specificity | TISSUE SPECIFICITY: Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle. {ECO:0000269|PubMed:10381382}. | ||||||||||
Sequence |
|
||||||||||
Sequence length | 498 | ||||||||||
Interactions | View interactions |