Gene Gene information from NCBI Gene database.
Entrez ID 7314
Gene name Ubiquitin B
Gene symbol UBB
Synonyms (NCBI Gene)
HEL-S-50
Chromosome 17
Chromosome location 17p11.2
Summary This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene e
miRNA miRNA information provided by mirtarbase database.
376
miRTarBase ID miRNA Experiments Reference
MIRT029681 hsa-miR-26b-5p Microarray 19088304
MIRT048633 hsa-miR-99a-5p CLASH 23622248
MIRT048512 hsa-miR-100-5p CLASH 23622248
MIRT047262 hsa-miR-181b-5p CLASH 23622248
MIRT040746 hsa-miR-18a-3p CLASH 23622248
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
HSF1 Unknown 20692357
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
43
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 14755250, 14764729, 15039775, 15143060, 15308666, 16189514, 16286470, 16499958, 17310990, 17662948, 17719543, 18029035, 18313049, 20924359, 21516116, 24981860, 28514442, 32296183, 32814053, 33961781
GO:0005615 Component Extracellular space HDA 16502470
GO:0005634 Component Nucleus HDA 21630459
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
191339 12463 ENSG00000170315
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P0CG47
Protein name Polyubiquitin-B [Cleaved into: Ubiquitin]
Protein function [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys re
PDB 2KHW , 2MBB , 2MRO , 2MSG , 2N13 , 4UEL , 4UF6 , 4WHV , 4WLR , 4WUR , 4XOF , 4ZFR , 4ZFT , 4ZPZ , 4ZUX , 5BNB , 5CAW , 5CRA , 5CVM , 5CVN , 5CVO , 5D0K , 5D0M , 5DFL , 5DK8 , 5E6J , 5EDV , 5EMZ , 5EYA , 5GJQ , 5GO7 , 5GO8 , 5GOB , 5GOC , 5GOD , 5GOG , 5GOH , 5GOI , 5GOJ , 5GOK , 5H7S , 5IBK , 5IFR , 5JBY , 5JG6 , 5JP3 , 5JTJ , 5JTV , 5K9P , 5KGF , 5KHY
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00240 ubiquitin 3 74 Ubiquitin family Domain
PF00240 ubiquitin 79 150 Ubiquitin family Domain
PF00240 ubiquitin 155 226 Ubiquitin family Domain
Sequence
Sequence length 229
Interactions View interactions