Gene Gene information from NCBI Gene database.
Entrez ID 7311
Gene name Ubiquitin A-52 residue ribosomal protein fusion product 1
Gene symbol UBA52
Synonyms (NCBI Gene)
CEP52HUBCEP52L40RPL40
Chromosome 19
Chromosome location 19p13.11
Summary Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, a
miRNA miRNA information provided by mirtarbase database.
466
miRTarBase ID miRNA Experiments Reference
MIRT051853 hsa-let-7c-5p CLASH 23622248
MIRT045345 hsa-miR-185-5p CLASH 23622248
MIRT044819 hsa-miR-320a CLASH 23622248
MIRT043902 hsa-miR-378a-3p CLASH 23622248
MIRT041941 hsa-miR-484 CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
42
GO ID Ontology Definition Evidence Reference
GO:0002181 Process Cytoplasmic translation IC 23636399
GO:0002181 Process Cytoplasmic translation IDA 39048817
GO:0002181 Process Cytoplasmic translation NAS 25901680
GO:0003735 Function Structural constituent of ribosome IBA
GO:0003735 Function Structural constituent of ribosome IDA 23636399, 32669547, 39048817
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
191321 12458 ENSG00000221983
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P62987
Protein name Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40) (rpL40)]
Protein function [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys re
PDB 2LJ5 , 2MBH , 2MJB , 2MUR , 2N3U , 2N3V , 2N3W , 2NBD , 2NBE , 2RSU , 4HJK , 4JIO , 4P4H , 4PIG , 4PIH , 4PIJ , 4RF0 , 4RF1 , 4S1Z , 4UG0 , 4V6X , 4XKL , 5AJ0 , 5GO7 , 5GO8 , 5GOB , 5GOC , 5GOD , 5GOG , 5GOH , 5GOI , 5GOJ , 5GOK , 5HPK , 5HPL , 5HPS , 5HPT , 5J26 , 5J8P , 5JBV , 5JBY , 5LKS , 5T2C , 6IP5 , 6IP6 , 6IP8 , 6LQM , 6OLE , 6OLF , 6OLG , 6OLI
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00240 ubiquitin 3 74 Ubiquitin family Domain
PF01020 Ribosomal_L40e 78 127 Ribosomal L40e family Family
Sequence
Sequence length 128
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Melanoma Uncertain significance rs760355792 RCV005926934
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 38095634
Alzheimer Disease Associate 32812532
Arthritis Rheumatoid Associate 39342401
Asthma Associate 35751199
Carcinoma Hepatocellular Associate 22258406
Carcinoma Squamous Cell Associate 33399095
Cognition Disorders Associate 32812532
Colorectal Neoplasms Associate 30690837
Complement Component C1s Deficiency Associate 31537905
COVID 19 Associate 35751199