Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	29896
Gene name Gene Name - the full gene name approved by the HGNC.	Transformer 2 alpha homolog
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TRA2A
Synonyms (NCBI Gene) Gene synonyms aliases	AWMS1, HSU53209
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p15.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing.

Show/Hide all(216)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016048	hsa-miR-374b-5p	Sequencing	20371350
MIRT047833	hsa-miR-30c-5p	CLASH	23622248
MIRT042676	hsa-miR-196b-5p	CLASH	23622248
MIRT1450539	hsa-miR-142-5p	CLIP-seq
MIRT1450540	hsa-miR-1468	CLIP-seq
MIRT1450541	hsa-miR-2110	CLIP-seq
MIRT1450542	hsa-miR-216a	CLIP-seq
MIRT1450543	hsa-miR-302f	CLIP-seq
MIRT1450544	hsa-miR-3120-3p	CLIP-seq
MIRT1450545	hsa-miR-3150a-3p	CLIP-seq
MIRT1450546	hsa-miR-3152-3p	CLIP-seq
MIRT1450547	hsa-miR-3171	CLIP-seq
MIRT1450548	hsa-miR-3607-5p	CLIP-seq
MIRT1450549	hsa-miR-3671	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT1450551	hsa-miR-4271	CLIP-seq
MIRT1450552	hsa-miR-4307	CLIP-seq
MIRT1450553	hsa-miR-4330	CLIP-seq
MIRT1450554	hsa-miR-4433	CLIP-seq
MIRT1450555	hsa-miR-4453	CLIP-seq
MIRT1450556	hsa-miR-4457	CLIP-seq
MIRT1450557	hsa-miR-4538	CLIP-seq
MIRT1450558	hsa-miR-4700-3p	CLIP-seq
MIRT1450559	hsa-miR-4725-3p	CLIP-seq
MIRT1450560	hsa-miR-5095	CLIP-seq
MIRT1450561	hsa-miR-513b	CLIP-seq
MIRT1450562	hsa-miR-561	CLIP-seq
MIRT1450563	hsa-miR-606	CLIP-seq
MIRT1450564	hsa-miR-607	CLIP-seq
MIRT1450540	hsa-miR-1468	CLIP-seq
MIRT1450543	hsa-miR-302f	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT1450552	hsa-miR-4307	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT1450554	hsa-miR-4433	CLIP-seq
MIRT1450556	hsa-miR-4457	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT1450558	hsa-miR-4700-3p	CLIP-seq
MIRT1450560	hsa-miR-5095	CLIP-seq
MIRT1450561	hsa-miR-513b	CLIP-seq
MIRT2134678	hsa-miR-548ae	CLIP-seq
MIRT2134679	hsa-miR-548aj	CLIP-seq
MIRT2134680	hsa-miR-548am	CLIP-seq
MIRT2134681	hsa-miR-548x	CLIP-seq
MIRT1450540	hsa-miR-1468	CLIP-seq
MIRT1450543	hsa-miR-302f	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT2649402	hsa-miR-101	CLIP-seq
MIRT2649403	hsa-miR-1293	CLIP-seq
MIRT1450539	hsa-miR-142-5p	CLIP-seq
MIRT2649404	hsa-miR-144	CLIP-seq
MIRT1450541	hsa-miR-2110	CLIP-seq
MIRT1450542	hsa-miR-216a	CLIP-seq
MIRT2649405	hsa-miR-2355-5p	CLIP-seq
MIRT2649406	hsa-miR-300	CLIP-seq
MIRT1450544	hsa-miR-3120-3p	CLIP-seq
MIRT2649407	hsa-miR-3124-3p	CLIP-seq
MIRT2649408	hsa-miR-3136-5p	CLIP-seq
MIRT2649409	hsa-miR-3143	CLIP-seq
MIRT2649410	hsa-miR-3146	CLIP-seq
MIRT2649411	hsa-miR-3148	CLIP-seq
MIRT1450545	hsa-miR-3150a-3p	CLIP-seq
MIRT1450546	hsa-miR-3152-3p	CLIP-seq
MIRT2649412	hsa-miR-3163	CLIP-seq
MIRT2649413	hsa-miR-3170	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT2649414	hsa-miR-323b-3p	CLIP-seq
MIRT2649415	hsa-miR-330-3p	CLIP-seq
MIRT1450548	hsa-miR-3607-5p	CLIP-seq
MIRT2649416	hsa-miR-3613-3p	CLIP-seq
MIRT2649417	hsa-miR-3653	CLIP-seq
MIRT2649418	hsa-miR-3658	CLIP-seq
MIRT2649419	hsa-miR-3662	CLIP-seq
MIRT2649420	hsa-miR-3672	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT2649421	hsa-miR-3679-3p	CLIP-seq
MIRT2649422	hsa-miR-3689a-5p	CLIP-seq
MIRT2649423	hsa-miR-3689b	CLIP-seq
MIRT2649424	hsa-miR-3689e	CLIP-seq
MIRT2649425	hsa-miR-3689f	CLIP-seq
MIRT2649426	hsa-miR-369-3p	CLIP-seq
MIRT2649427	hsa-miR-374a	CLIP-seq
MIRT2649428	hsa-miR-374b	CLIP-seq
MIRT2649429	hsa-miR-374c	CLIP-seq
MIRT2649430	hsa-miR-381	CLIP-seq
MIRT2649431	hsa-miR-3935	CLIP-seq
MIRT2649432	hsa-miR-4263	CLIP-seq
MIRT1450551	hsa-miR-4271	CLIP-seq
MIRT2649433	hsa-miR-4275	CLIP-seq
MIRT2649434	hsa-miR-4280	CLIP-seq
MIRT2649435	hsa-miR-4282	CLIP-seq
MIRT2649436	hsa-miR-4286	CLIP-seq
MIRT2649437	hsa-miR-433	CLIP-seq
MIRT1450553	hsa-miR-4330	CLIP-seq
MIRT2649438	hsa-miR-4422	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT2649439	hsa-miR-4439	CLIP-seq
MIRT2649440	hsa-miR-4446-5p	CLIP-seq
MIRT1450555	hsa-miR-4453	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT2649441	hsa-miR-4483	CLIP-seq
MIRT2649442	hsa-miR-4501	CLIP-seq
MIRT2649443	hsa-miR-4506	CLIP-seq
MIRT2649444	hsa-miR-4513	CLIP-seq
MIRT1450557	hsa-miR-4538	CLIP-seq
MIRT2649445	hsa-miR-4539	CLIP-seq
MIRT2649446	hsa-miR-4666-3p	CLIP-seq
MIRT2649447	hsa-miR-4698	CLIP-seq
MIRT2649448	hsa-miR-4724-5p	CLIP-seq
MIRT1450559	hsa-miR-4725-3p	CLIP-seq
MIRT2649449	hsa-miR-4789-5p	CLIP-seq
MIRT2649450	hsa-miR-4803	CLIP-seq
MIRT2649451	hsa-miR-490-3p	CLIP-seq
MIRT2649452	hsa-miR-513a-3p	CLIP-seq
MIRT2649453	hsa-miR-520d-5p	CLIP-seq
MIRT2649454	hsa-miR-524-5p	CLIP-seq
MIRT2649455	hsa-miR-543	CLIP-seq
MIRT2649456	hsa-miR-548p	CLIP-seq
MIRT2649457	hsa-miR-548t	CLIP-seq
MIRT2649458	hsa-miR-549	CLIP-seq
MIRT1450562	hsa-miR-561	CLIP-seq
MIRT2649459	hsa-miR-570	CLIP-seq
MIRT2649460	hsa-miR-576-5p	CLIP-seq
MIRT1450563	hsa-miR-606	CLIP-seq
MIRT2649461	hsa-miR-649	CLIP-seq
MIRT2649462	hsa-miR-655	CLIP-seq
MIRT2649463	hsa-miR-888	CLIP-seq
MIRT2649402	hsa-miR-101	CLIP-seq
MIRT2649403	hsa-miR-1293	CLIP-seq
MIRT1450539	hsa-miR-142-5p	CLIP-seq
MIRT2649404	hsa-miR-144	CLIP-seq
MIRT1450541	hsa-miR-2110	CLIP-seq
MIRT1450542	hsa-miR-216a	CLIP-seq
MIRT2649405	hsa-miR-2355-5p	CLIP-seq
MIRT1450544	hsa-miR-3120-3p	CLIP-seq
MIRT2649407	hsa-miR-3124-3p	CLIP-seq
MIRT2649408	hsa-miR-3136-5p	CLIP-seq
MIRT2649409	hsa-miR-3143	CLIP-seq
MIRT2649410	hsa-miR-3146	CLIP-seq
MIRT2649411	hsa-miR-3148	CLIP-seq
MIRT1450545	hsa-miR-3150a-3p	CLIP-seq
MIRT1450546	hsa-miR-3152-3p	CLIP-seq
MIRT2649412	hsa-miR-3163	CLIP-seq
MIRT2649413	hsa-miR-3170	CLIP-seq
MIRT1450547	hsa-miR-3171	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT2649414	hsa-miR-323b-3p	CLIP-seq
MIRT2649415	hsa-miR-330-3p	CLIP-seq
MIRT1450548	hsa-miR-3607-5p	CLIP-seq
MIRT2649416	hsa-miR-3613-3p	CLIP-seq
MIRT2649417	hsa-miR-3653	CLIP-seq
MIRT2649418	hsa-miR-3658	CLIP-seq
MIRT2649419	hsa-miR-3662	CLIP-seq
MIRT1450549	hsa-miR-3671	CLIP-seq
MIRT2649420	hsa-miR-3672	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT2649421	hsa-miR-3679-3p	CLIP-seq
MIRT2649422	hsa-miR-3689a-5p	CLIP-seq
MIRT2649423	hsa-miR-3689b	CLIP-seq
MIRT2649424	hsa-miR-3689e	CLIP-seq
MIRT2649425	hsa-miR-3689f	CLIP-seq
MIRT2649426	hsa-miR-369-3p	CLIP-seq
MIRT2649427	hsa-miR-374a	CLIP-seq
MIRT2649428	hsa-miR-374b	CLIP-seq
MIRT2649429	hsa-miR-374c	CLIP-seq
MIRT2649431	hsa-miR-3935	CLIP-seq
MIRT2649432	hsa-miR-4263	CLIP-seq
MIRT1450551	hsa-miR-4271	CLIP-seq
MIRT2649433	hsa-miR-4275	CLIP-seq
MIRT2649434	hsa-miR-4280	CLIP-seq
MIRT2649435	hsa-miR-4282	CLIP-seq
MIRT2649436	hsa-miR-4286	CLIP-seq
MIRT2649437	hsa-miR-433	CLIP-seq
MIRT1450553	hsa-miR-4330	CLIP-seq
MIRT2649438	hsa-miR-4422	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT2649439	hsa-miR-4439	CLIP-seq
MIRT2649440	hsa-miR-4446-5p	CLIP-seq
MIRT1450555	hsa-miR-4453	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT2649441	hsa-miR-4483	CLIP-seq
MIRT2649442	hsa-miR-4501	CLIP-seq
MIRT2649443	hsa-miR-4506	CLIP-seq
MIRT2649444	hsa-miR-4513	CLIP-seq
MIRT1450557	hsa-miR-4538	CLIP-seq
MIRT2649445	hsa-miR-4539	CLIP-seq
MIRT2649448	hsa-miR-4724-5p	CLIP-seq
MIRT1450559	hsa-miR-4725-3p	CLIP-seq
MIRT2649450	hsa-miR-4803	CLIP-seq
MIRT2649451	hsa-miR-490-3p	CLIP-seq
MIRT2649452	hsa-miR-513a-3p	CLIP-seq
MIRT2649453	hsa-miR-520d-5p	CLIP-seq
MIRT2649454	hsa-miR-524-5p	CLIP-seq
MIRT2649455	hsa-miR-543	CLIP-seq
MIRT2134678	hsa-miR-548ae	CLIP-seq
MIRT2134679	hsa-miR-548aj	CLIP-seq
MIRT2134680	hsa-miR-548am	CLIP-seq
MIRT2649456	hsa-miR-548p	CLIP-seq
MIRT2649457	hsa-miR-548t	CLIP-seq
MIRT2134681	hsa-miR-548x	CLIP-seq
MIRT2649458	hsa-miR-549	CLIP-seq
MIRT1450562	hsa-miR-561	CLIP-seq
MIRT2649459	hsa-miR-570	CLIP-seq
MIRT2649460	hsa-miR-576-5p	CLIP-seq
MIRT1450563	hsa-miR-606	CLIP-seq
MIRT1450564	hsa-miR-607	CLIP-seq
MIRT2649461	hsa-miR-649	CLIP-seq
MIRT2649462	hsa-miR-655	CLIP-seq
MIRT2649463	hsa-miR-888	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	9546399
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IDA	9546399
GO:0005654	Component	Nucleoplasm	IDA
GO:0005681	Component	Spliceosomal complex	IBA	21873635
GO:0005730	Component	Nucleolus	IDA
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA
GO:0048026	Process	Positive regulation of mRNA splicing, via spliceosome	IBA	21873635

MIM	HGNC	e!Ensembl
602718	16645	ENSG00000164548

Protein

UniProt ID

Q13595

Protein name

Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)

Protein function

Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	121 → 191	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Sequence

MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRS
RRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTC
LGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERA
NGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRRRDSYYDR
GYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPRRY

Sequence length

282

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Schizophrenia	Schizophrenia	GWAS
Diabetes	Diabetes	GWAS

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	32372707
Carcinoma Hepatocellular	Associate	37564197
Hypoxia	Stimulate	35635094
Ovarian Neoplasms	Associate	23748175
Pancreatic Neoplasms	Associate	35635094
Prostatic Neoplasms	Associate	28403887

TRA2A (transformer 2 alpha homolog)