TRA2A (transformer 2 alpha homolog)

Gene

• Entrez ID: 29896
• Gene name: Transformer 2 alpha homolog
• Gene symbol: TRA2A
• Synonyms (NCBI Gene): AWMS1, HSU53209
• Chromosome: 7
• Chromosome location: 7p15.3
• Summary: This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing.

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016048	hsa-miR-374b-5p	Sequencing	20371350
MIRT047833	hsa-miR-30c-5p	CLASH	23622248
MIRT042676	hsa-miR-196b-5p	CLASH	23622248
MIRT1450539	hsa-miR-142-5p	CLIP-seq
MIRT1450540	hsa-miR-1468	CLIP-seq
MIRT1450541	hsa-miR-2110	CLIP-seq
MIRT1450542	hsa-miR-216a	CLIP-seq
MIRT1450543	hsa-miR-302f	CLIP-seq
MIRT1450544	hsa-miR-3120-3p	CLIP-seq
MIRT1450545	hsa-miR-3150a-3p	CLIP-seq
MIRT1450546	hsa-miR-3152-3p	CLIP-seq
MIRT1450547	hsa-miR-3171	CLIP-seq
MIRT1450548	hsa-miR-3607-5p	CLIP-seq
MIRT1450549	hsa-miR-3671	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT1450551	hsa-miR-4271	CLIP-seq
MIRT1450552	hsa-miR-4307	CLIP-seq
MIRT1450553	hsa-miR-4330	CLIP-seq
MIRT1450554	hsa-miR-4433	CLIP-seq
MIRT1450555	hsa-miR-4453	CLIP-seq
MIRT1450556	hsa-miR-4457	CLIP-seq
MIRT1450557	hsa-miR-4538	CLIP-seq
MIRT1450558	hsa-miR-4700-3p	CLIP-seq
MIRT1450559	hsa-miR-4725-3p	CLIP-seq
MIRT1450560	hsa-miR-5095	CLIP-seq
MIRT1450561	hsa-miR-513b	CLIP-seq
MIRT1450562	hsa-miR-561	CLIP-seq
MIRT1450563	hsa-miR-606	CLIP-seq
MIRT1450564	hsa-miR-607	CLIP-seq
MIRT1450540	hsa-miR-1468	CLIP-seq
MIRT1450543	hsa-miR-302f	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT1450552	hsa-miR-4307	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT1450554	hsa-miR-4433	CLIP-seq
MIRT1450556	hsa-miR-4457	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT1450558	hsa-miR-4700-3p	CLIP-seq
MIRT1450560	hsa-miR-5095	CLIP-seq
MIRT1450561	hsa-miR-513b	CLIP-seq
MIRT2134678	hsa-miR-548ae	CLIP-seq
MIRT2134679	hsa-miR-548aj	CLIP-seq
MIRT2134680	hsa-miR-548am	CLIP-seq
MIRT2134681	hsa-miR-548x	CLIP-seq
MIRT1450540	hsa-miR-1468	CLIP-seq
MIRT1450543	hsa-miR-302f	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT2649402	hsa-miR-101	CLIP-seq
MIRT2649403	hsa-miR-1293	CLIP-seq
MIRT1450539	hsa-miR-142-5p	CLIP-seq
MIRT2649404	hsa-miR-144	CLIP-seq
MIRT1450541	hsa-miR-2110	CLIP-seq
MIRT1450542	hsa-miR-216a	CLIP-seq
MIRT2649405	hsa-miR-2355-5p	CLIP-seq
MIRT2649406	hsa-miR-300	CLIP-seq
MIRT1450544	hsa-miR-3120-3p	CLIP-seq
MIRT2649407	hsa-miR-3124-3p	CLIP-seq
MIRT2649408	hsa-miR-3136-5p	CLIP-seq
MIRT2649409	hsa-miR-3143	CLIP-seq
MIRT2649410	hsa-miR-3146	CLIP-seq
MIRT2649411	hsa-miR-3148	CLIP-seq
MIRT1450545	hsa-miR-3150a-3p	CLIP-seq
MIRT1450546	hsa-miR-3152-3p	CLIP-seq
MIRT2649412	hsa-miR-3163	CLIP-seq
MIRT2649413	hsa-miR-3170	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT2649414	hsa-miR-323b-3p	CLIP-seq
MIRT2649415	hsa-miR-330-3p	CLIP-seq
MIRT1450548	hsa-miR-3607-5p	CLIP-seq
MIRT2649416	hsa-miR-3613-3p	CLIP-seq
MIRT2649417	hsa-miR-3653	CLIP-seq
MIRT2649418	hsa-miR-3658	CLIP-seq
MIRT2649419	hsa-miR-3662	CLIP-seq
MIRT2649420	hsa-miR-3672	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT2649421	hsa-miR-3679-3p	CLIP-seq
MIRT2649422	hsa-miR-3689a-5p	CLIP-seq
MIRT2649423	hsa-miR-3689b	CLIP-seq
MIRT2649424	hsa-miR-3689e	CLIP-seq
MIRT2649425	hsa-miR-3689f	CLIP-seq
MIRT2649426	hsa-miR-369-3p	CLIP-seq
MIRT2649427	hsa-miR-374a	CLIP-seq
MIRT2649428	hsa-miR-374b	CLIP-seq
MIRT2649429	hsa-miR-374c	CLIP-seq
MIRT2649430	hsa-miR-381	CLIP-seq
MIRT2649431	hsa-miR-3935	CLIP-seq
MIRT2649432	hsa-miR-4263	CLIP-seq
MIRT1450551	hsa-miR-4271	CLIP-seq
MIRT2649433	hsa-miR-4275	CLIP-seq
MIRT2649434	hsa-miR-4280	CLIP-seq
MIRT2649435	hsa-miR-4282	CLIP-seq
MIRT2649436	hsa-miR-4286	CLIP-seq
MIRT2649437	hsa-miR-433	CLIP-seq
MIRT1450553	hsa-miR-4330	CLIP-seq
MIRT2649438	hsa-miR-4422	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT2649439	hsa-miR-4439	CLIP-seq
MIRT2649440	hsa-miR-4446-5p	CLIP-seq
MIRT1450555	hsa-miR-4453	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT2649441	hsa-miR-4483	CLIP-seq
MIRT2649442	hsa-miR-4501	CLIP-seq
MIRT2649443	hsa-miR-4506	CLIP-seq
MIRT2649444	hsa-miR-4513	CLIP-seq
MIRT1450557	hsa-miR-4538	CLIP-seq
MIRT2649445	hsa-miR-4539	CLIP-seq
MIRT2649446	hsa-miR-4666-3p	CLIP-seq
MIRT2649447	hsa-miR-4698	CLIP-seq
MIRT2649448	hsa-miR-4724-5p	CLIP-seq
MIRT1450559	hsa-miR-4725-3p	CLIP-seq
MIRT2649449	hsa-miR-4789-5p	CLIP-seq
MIRT2649450	hsa-miR-4803	CLIP-seq
MIRT2649451	hsa-miR-490-3p	CLIP-seq
MIRT2649452	hsa-miR-513a-3p	CLIP-seq
MIRT2649453	hsa-miR-520d-5p	CLIP-seq
MIRT2649454	hsa-miR-524-5p	CLIP-seq
MIRT2649455	hsa-miR-543	CLIP-seq
MIRT2649456	hsa-miR-548p	CLIP-seq
MIRT2649457	hsa-miR-548t	CLIP-seq
MIRT2649458	hsa-miR-549	CLIP-seq
MIRT1450562	hsa-miR-561	CLIP-seq
MIRT2649459	hsa-miR-570	CLIP-seq
MIRT2649460	hsa-miR-576-5p	CLIP-seq
MIRT1450563	hsa-miR-606	CLIP-seq
MIRT2649461	hsa-miR-649	CLIP-seq
MIRT2649462	hsa-miR-655	CLIP-seq
MIRT2649463	hsa-miR-888	CLIP-seq
MIRT2649402	hsa-miR-101	CLIP-seq
MIRT2649403	hsa-miR-1293	CLIP-seq
MIRT1450539	hsa-miR-142-5p	CLIP-seq
MIRT2649404	hsa-miR-144	CLIP-seq
MIRT1450541	hsa-miR-2110	CLIP-seq
MIRT1450542	hsa-miR-216a	CLIP-seq
MIRT2649405	hsa-miR-2355-5p	CLIP-seq
MIRT1450544	hsa-miR-3120-3p	CLIP-seq
MIRT2649407	hsa-miR-3124-3p	CLIP-seq
MIRT2649408	hsa-miR-3136-5p	CLIP-seq
MIRT2649409	hsa-miR-3143	CLIP-seq
MIRT2649410	hsa-miR-3146	CLIP-seq
MIRT2649411	hsa-miR-3148	CLIP-seq
MIRT1450545	hsa-miR-3150a-3p	CLIP-seq
MIRT1450546	hsa-miR-3152-3p	CLIP-seq
MIRT2649412	hsa-miR-3163	CLIP-seq
MIRT2649413	hsa-miR-3170	CLIP-seq
MIRT1450547	hsa-miR-3171	CLIP-seq
MIRT2134674	hsa-miR-3173-3p	CLIP-seq
MIRT2649414	hsa-miR-323b-3p	CLIP-seq
MIRT2649415	hsa-miR-330-3p	CLIP-seq
MIRT1450548	hsa-miR-3607-5p	CLIP-seq
MIRT2649416	hsa-miR-3613-3p	CLIP-seq
MIRT2649417	hsa-miR-3653	CLIP-seq
MIRT2649418	hsa-miR-3658	CLIP-seq
MIRT2649419	hsa-miR-3662	CLIP-seq
MIRT1450549	hsa-miR-3671	CLIP-seq
MIRT2649420	hsa-miR-3672	CLIP-seq
MIRT1450550	hsa-miR-3675-3p	CLIP-seq
MIRT2649421	hsa-miR-3679-3p	CLIP-seq
MIRT2649422	hsa-miR-3689a-5p	CLIP-seq
MIRT2649423	hsa-miR-3689b	CLIP-seq
MIRT2649424	hsa-miR-3689e	CLIP-seq
MIRT2649425	hsa-miR-3689f	CLIP-seq
MIRT2649426	hsa-miR-369-3p	CLIP-seq
MIRT2649427	hsa-miR-374a	CLIP-seq
MIRT2649428	hsa-miR-374b	CLIP-seq
MIRT2649429	hsa-miR-374c	CLIP-seq
MIRT2649431	hsa-miR-3935	CLIP-seq
MIRT2649432	hsa-miR-4263	CLIP-seq
MIRT1450551	hsa-miR-4271	CLIP-seq
MIRT2649433	hsa-miR-4275	CLIP-seq
MIRT2649434	hsa-miR-4280	CLIP-seq
MIRT2649435	hsa-miR-4282	CLIP-seq
MIRT2649436	hsa-miR-4286	CLIP-seq
MIRT2649437	hsa-miR-433	CLIP-seq
MIRT1450553	hsa-miR-4330	CLIP-seq
MIRT2649438	hsa-miR-4422	CLIP-seq
MIRT2134675	hsa-miR-4428	CLIP-seq
MIRT2649439	hsa-miR-4439	CLIP-seq
MIRT2649440	hsa-miR-4446-5p	CLIP-seq
MIRT1450555	hsa-miR-4453	CLIP-seq
MIRT2134676	hsa-miR-4476	CLIP-seq
MIRT2134677	hsa-miR-4477b	CLIP-seq
MIRT2649441	hsa-miR-4483	CLIP-seq
MIRT2649442	hsa-miR-4501	CLIP-seq
MIRT2649443	hsa-miR-4506	CLIP-seq
MIRT2649444	hsa-miR-4513	CLIP-seq
MIRT1450557	hsa-miR-4538	CLIP-seq
MIRT2649445	hsa-miR-4539	CLIP-seq
MIRT2649448	hsa-miR-4724-5p	CLIP-seq
MIRT1450559	hsa-miR-4725-3p	CLIP-seq
MIRT2649450	hsa-miR-4803	CLIP-seq
MIRT2649451	hsa-miR-490-3p	CLIP-seq
MIRT2649452	hsa-miR-513a-3p	CLIP-seq
MIRT2649453	hsa-miR-520d-5p	CLIP-seq
MIRT2649454	hsa-miR-524-5p	CLIP-seq
MIRT2649455	hsa-miR-543	CLIP-seq
MIRT2134678	hsa-miR-548ae	CLIP-seq
MIRT2134679	hsa-miR-548aj	CLIP-seq
MIRT2134680	hsa-miR-548am	CLIP-seq
MIRT2649456	hsa-miR-548p	CLIP-seq
MIRT2649457	hsa-miR-548t	CLIP-seq
MIRT2134681	hsa-miR-548x	CLIP-seq
MIRT2649458	hsa-miR-549	CLIP-seq
MIRT1450562	hsa-miR-561	CLIP-seq
MIRT2649459	hsa-miR-570	CLIP-seq
MIRT2649460	hsa-miR-576-5p	CLIP-seq
MIRT1450563	hsa-miR-606	CLIP-seq
MIRT1450564	hsa-miR-607	CLIP-seq
MIRT2649461	hsa-miR-649	CLIP-seq
MIRT2649462	hsa-miR-655	CLIP-seq
MIRT2649463	hsa-miR-888	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	9546399
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	23602568, 32296183, 32707033, 33961781, 39251607
GO:0005634	Component	Nucleus	IDA	9546399
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005681	Component	Spliceosomal complex	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0048026	Process	Positive regulation of mRNA splicing, via spliceosome	IBA

Other IDs

• MIM: 602718
• HGNC: 16645
• e!Ensembl: ENSG00000164548

Protein

• UniProt ID: Q13595
• Protein name: Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
• Protein function: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00076	RRM_1	121 → 191	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

• Sequence:

  MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRS
  RRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTC
  LGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERA
  NGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRRRDSYYDR
  GYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPRRY

• Sequence length: 282