TPM4 (tropomyosin 4)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7171 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Tropomyosin 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TPM4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BDPLT25, HEL-S-108 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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BDPLT25 |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.12-p13.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end- |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P67936 | ||||||||||
Protein name | Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4) | ||||||||||
Protein function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by int | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy tha | ||||||||||
Sequence |
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Sequence length | 248 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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